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Arrhythmias, Electrophysiology, and Electrocardiography

Determinants of Short-Period Heart Rate Variability in the General Population

Kuch B.a,c · Hense H.W.a · Sinnreich R.d · Kark J.D.d · von Eckardstein A.b · Sapoznikov D.d · Bolte H.-D.c

Author affiliations

aInstitute of Epidemiology and Social Medicine and bInstitute of Clinical Chemistry and Laboratory Medicine, University of Münster, and cDepartment of Medicine I, Central Hospital Augsburg, Academic Training Clinic University Munich, Germany; dDepartment of Social Medicine and Department of Cardiology, Hadassah Medical Organization and Hebrew University-Hadassah School of Public Health, Jerusalem, Israel

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Cardiology 2001;95:131–138

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Article / Publication Details

First-Page Preview
Abstract of Arrhythmias, Electrophysiology, and Electrocardiography

Published online: July 20, 2001
Issue release date: July 2001

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 6

ISSN: 0008-6312 (Print)
eISSN: 1421-9751 (Online)

For additional information: https://www.karger.com/CRD

Abstract

Decreased heart rate variability (HRV) is associated with a worse prognosis in a variety of diseases and disorders. We evaluated the determinants of short-period HRV in a random sample of 149 middle-aged men and 137 women from the general population. Spectral analysis was used to compute low-frequency (LF), high-frequency (HF) and total-frequency power. HRV showed a strong inverse association with age and heart rate in both sexes with a more pronounced effect of heart rate on HRV in women. Age and heart rate-adjusted LF was significantly higher in men and HF higher in women. Significant negative correlations of BMI, triglycerides, insulin and positive correlations of HDL cholesterol with LF and total power occurred only in men. In multivariate analyses, heart rate and age persisted as prominent independent predictors of HRV. In addition, BMI was strongly negatively associated with LF in men but not in women. We conclude that the more pronounced vagal influence in cardiac regulation in middle-aged women and the gender-different influence of heart rate and metabolic factors on HRV may help to explain the lower susceptibility of women for cardiac arrhythmias.

© 2001 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Arrhythmias, Electrophysiology, and Electrocardiography

Published online: July 20, 2001
Issue release date: July 2001

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 6

ISSN: 0008-6312 (Print)
eISSN: 1421-9751 (Online)

For additional information: https://www.karger.com/CRD


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