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Original Paper

Dental Amalgam Fillings and the Amount of Organic Mercury in Human Saliva

Leistevuo J.a,b · Leistevuo T.d · Helenius H.c · Pyy L.e · Österblad M.a · Huovinen P.a · Tenovuo J.b

Author affiliations

aThe National Public Health Institute, Antimicrobial Research Laboratory; bInstitute of Dentistry and cDepartment of Biostatistics, Turku University, and dDepartment of Physical Medicine and Rehabilitation, Turku University Hospital, Turku, Finland; eOulu Regional Institute of Occupational Health, Oulu, Finland

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Caries Res 2001;35:163–166

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: May 24, 2001
Issue release date: May – June

Number of Print Pages: 4
Number of Figures: 1
Number of Tables: 1

ISSN: 0008-6568 (Print)
eISSN: 1421-976X (Online)

For additional information: https://www.karger.com/CRE

Abstract

We studied differences in the amounts of organic and inorganic mercury in saliva samples between amalgam and nonamalgam human study groups. The amount of organic and inorganic mercury in whole saliva was measured in 187 adult study subjects. The mercury contents were determined by cold–vapor atomic absorption spectrometry. The amount of organic and inorganic mercury in paraffin–stimulated saliva was significantly higher (p<0.001) in subjects with dental amalgam fillings (n = 88) compared to the nonamalgam study groups (n = 43 and n = 56): loge (organic mercury) was linearly related to loge (inorganic mercury, r2 = 0.52). Spearman correlation coefficients of inorganic and organic mercury concentrations with the number of amalgam–filled tooth surfaces were 0.46 and 0.27, respectively. Our results are compatible with the hypothesis that amalgam fillings may be a continuous source of organic mercury, which is more toxic than inorganic mercury, and almost completely absorbed by the human intestine.


References

  1. Björkman L, Sandborgh–Englund G, Ekstrand J: Mercury in saliva and feces after removal of amalgam fillings. Toxicol Appl Pharmacol 1997;144:156–162.
  2. Edlund C, Björkman L, Ekstrand J, Sandborgh–Englund G, Nord CE: Resistance of the normal human microflora to mercury and antimicrobials after exposure to mercury from dental amalgam fillings. Clin Infect Dis 1996;22: 944–950.
    External Resources
  3. Gay DD, Cox RD, Reinhardt JW: Chewing releases mercury from fillings. Lancet 1979;i:985– 986.
  4. Goyer RA: Toxic effects of metals; in Klaasen CD (ed): Casarett and Doull’s Toxicology: The Basic Science of Poisons, ed 5. New York, McGraw–Hill, 1996, pp 709–711.
  5. Halbach S: Combined estimation of mercury species released from amalgam. J Dent Res 1995;74:1103–1109.
    External Resources
  6. Heintze U, Edwardsson S, Dérand T, Birkhed D: Methylation of mercury from dental amalgam and mercuric chloride by oral streptococci in vitro. Scand J Dent Res 1983;91:150–152.
  7. Lajunen L, Kinnunen A, Yrjänheikki E: Determination of mercury in blood and fish samples by cold–vapor atomic absorption and direct current plasma emission spectrometry. Atomic Spectrosc 1985;6:49–52.
  8. Lehmann EL: Nonparametrics: Statistical Methods Based on Ranks. San Francisco, Holden–Day, 1975.
  9. Mackey EA, Becker DA: Determination of methylmercury in two mussel tissue Standard Reference Materials by pre–irradiation separation and neutron activation analysis. Analyst 1998;123:779–783.
  10. Magos L, Cernic A: A rapid method for estimating mercury in undigested biological samples. Br J Ind Med 1969;26:144–149.
    External Resources
  11. Österblad M, Leistevuo J, Leistevuo T, Järvinen H, Pyy L, Tenovuo J, Huovinen P: Antimicrobial and mercury resistance in aerobic gram–negative bacilli in fecal flora among persons with and without dental amalgam fillings. Antimicrob Agents Chemother 1995;39:2499–2502.
    External Resources
  12. Ott KHR, Loh F, Kröncke A, Schaller K–H, Valentin H, Weltle D: Zur Quecksilberbelastung durch Amalgamfüllungen. Dtsch Zahnärztl Z 1984;39:199–205.
    External Resources
  13. WHO: IPCS. Environmental Health Criteria 101: Organic Mercury. Geneva, WHO, 1990, pp 3– 140.
  14. WHO: IPCS. Environmental Health Criteria 118: Inorganic Mercury. Geneva, WHO, 1991, pp 3–147.

Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: May 24, 2001
Issue release date: May – June

Number of Print Pages: 4
Number of Figures: 1
Number of Tables: 1

ISSN: 0008-6568 (Print)
eISSN: 1421-976X (Online)

For additional information: https://www.karger.com/CRE


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