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Clinical Practice: Mini-Review

Free Access

A Role of Remote Organs Effect in Acute Kidney Injury Outcome

Dépret F.a, b · Prud'homme M.b · Legrand M.a, b

Author affiliations

aDepartment of Anesthesiology and Critical Care and Burn Unit, AP-HP, St-Louis-Lariboisière Hospital, University Paris Diderot, and bINSERM UMR-S 942, Institute National de la Santé et de la Recherche Médicale (INSERM), Lariboisière Hospital, FCRIN INICRCT Network, Paris, France

Corresponding Author

Dr. Matthieu Legrand

Department of Anesthesiology and Critical Care and Burn Unit

St-Louis Hospital, Assistance Publique-Hôpitaux de Paris

1 Avenue Claude Vellefaux, FR-75010 (France)

E-Mail matthieu.legrand@aphp.fr

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Nephron 2017;137:273–276

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Acute kidney injury (AKI) has been associated with both short- and long-term outcomes. To date, there is still a debate whether the increase risk of morbidity and mortality is directly due to AKI occurrence. There is, however, a potential causal impact of AKI on outcome, but evidence of this association is yet lacking. The hypothesis of remote organ damage and dysfunction (heart, lung, liver, brain, etc.) has emerged over the last decade and may explain the reason for the potential negative impact of AKI on outcome. The aim of this review was to describe findings concerning the remote effect of AKI in animal models and human studies.

© 2017 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Clinical Practice: Mini-Review

Received: March 03, 2017
Accepted: April 21, 2017
Published online: June 07, 2017
Issue release date: December 2017

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

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