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Clinical Practice: Mini-Review

Free Access

Role of Immune Cells in Acute Kidney Injury and Repair

Lee S.A.a, c · Noel S.a · Sadasivam M.b · Hamad A.R.A.b · Rabb H.a

Author affiliations

aDepartment of Medicine, and bDepartment of Pathology, Johns Hopkins University, Baltimore, MD, USA; cYonsei University College of Medicine, Seoul, South Korea

Corresponding Author

Dr. Hamid Rabb

Department of Medicine, Johns Hopkins University

720 Rutland Avenue, Ross 965

Baltimore, MD 21205 (USA)

E-Mail hrabb1@jhmi.edu

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Nephron 2017;137:282–286

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Abstract

Acute kidney injury (AKI) is a significant problem in both native and transplant kidneys. There have been significant advances in understanding the role of immune cells in the early injury and repair from AKI. In this brief review, we aim to update information on the pathophysiologic impact of various immune cells in AKI, with special emphasis on repair. An improved understanding of the AKI immunopathology will lead to new therapies that prevent AKI, accelerate repair, and prevent the progression of AKI to chronic kidney disease.

© 2017 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Clinical Practice: Mini-Review

Received: April 04, 2017
Accepted: April 27, 2017
Published online: June 10, 2017
Issue release date: Published online first

Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 0

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: https://www.karger.com/NEF


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