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Clinical Practice: Mini-Review

Lymphocyte Function in Human Acute Kidney Injury

Weller S. · Varrier M. · Ostermann M.

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Department of Critical Care, King's College London School of Medical Education, Guy's and St Thomas' NHS Foundation Trust, London, UK

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Nephron 2017;137:287–293

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Article / Publication Details

First-Page Preview
Abstract of Clinical Practice: Mini-Review

Received: April 18, 2017
Accepted: June 09, 2017
Published online: June 30, 2017
Issue release date: Published online first

Number of Print Pages: 7
Number of Figures: 1
Number of Tables: 3

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: https://www.karger.com/NEF

Abstract

Acute kidney injury (AKI) has been recognised as an inflammatory condition with serious short- and long-term complications. Animal studies primarily using models of ischaemia reperfusion injury or caecal ligation and perforation have clearly demonstrated that inflammatory cells contribute to the initiation, propagation and recovery phase of AKI and that lymphocytes have a key role in these processes. Less is known about their involvement in common types of human AKI. This paper summarises the key findings of experimental AKI studies and limited human data with particular focus on the role of T-lymphocytes.

© 2017 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Clinical Practice: Mini-Review

Received: April 18, 2017
Accepted: June 09, 2017
Published online: June 30, 2017
Issue release date: Published online first

Number of Print Pages: 7
Number of Figures: 1
Number of Tables: 3

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: https://www.karger.com/NEF


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