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Original Paper

Variants in Chemosensory Genes Are Associated with Picky Eating Behavior in Preschool-Age Children

Cole N.C.a · Wang A.A.a · Donovan S.M.a, b · Lee S.-Y.a, b · Teran-Garcia M.a,c,d · the STRONG Kids Team

Author affiliations

aDivision of Nutritional Sciences, and Departments of bFood Science and Human Nutrition, and cHuman Development and Family Studies, and dCooperative Extension, University of Illinois, Urbana, IL, USA

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J Nutrigenet Nutrigenomics 2017;10:84-92

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: March 02, 2017
Accepted: June 02, 2017
Published online: August 31, 2017
Issue release date: November 2017

Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 4

ISSN: 1661-6499 (Print)
eISSN: 1661-6758 (Online)

For additional information: https://www.karger.com/JNN

Abstract

Background/Aims: Picky eating is prevalent among preschoolers and is associated with risk of both underweight and overweight. Although differences in taste perception may be due to genetic variation, it is unclear whether these variations are related to picky eating behavior. The aim of this study was to investigate the association of 6 single nucleotide polymorphisms (SNPs) in 5 candidate genes related to chemosensory perception with picky eating behavior and adiposity in a cohort of preschool-aged children. Methods: Parents of 2- to 5-year-old non-Hispanic white preschoolers (n = 153) responded to survey questions on demographics, and information regarding their child's breastfeeding history and picky eating behavior. Height and weight were measured to calculate body mass index (BMI) z-scores using standard growth charts, and saliva was collected for genotyping. Generalized linear models were used to examine associations between picky eating behavior and BMI z-scores with genetic variation. Results: When controlling for child age, sex, breastfed status, and parent education level, SNPs in TAS2R38 (rs713598) and CA6 (rs2274327) were associated with picky eating behavior in children. There was no association between SNPs and BMI z-scores. Conclusion: Genes related to chemosensory perception may play a role in children's picky eating behavior.

© 2017 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: March 02, 2017
Accepted: June 02, 2017
Published online: August 31, 2017
Issue release date: November 2017

Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 4

ISSN: 1661-6499 (Print)
eISSN: 1661-6758 (Online)

For additional information: https://www.karger.com/JNN


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