Stereotactic Biopsy for Intracranial Space-Occupying Lesions: Clinical Analysis of 550 CasesYu X.a · Liu Z.a · Tian Z.a · Li S.a · Huang H.a · Xiu B.a · Zhao Q.a · Liu L.b · Jing W.b
aDepartment of Neurosurgery, Navy General Hospital of PLA, Beijing, and bDepartment of Neurosurgery, Linfen City Hospital, Shanxi, China
Do you have an account?
- Rent for 48h to view
- Buy Cloud Access for unlimited viewing via different devices
- Synchronizing in the ReadCube Cloud
- Printing and saving restrictions apply
Rental: USD 8.50
Cloud: USD 20.00
Object: To investigate the role of stereotactic biopsy in planning the optimal management of intracranial space-occupying lesions. Patients and Methods: Between December 1989 and December 1999, stereotactic biopsy was performed in 550 patients with intracranial mass lesions that were deep-seated or located in the functional area. There were 340 males and 210 females, and their ages ranged from 4 to 75 years. All the procedures were done under local anesthesia with a Leksell stereotactic system. A CT scan was used to determine the coordinates in the first 420 cases and the Aero Tech Stereotactic Surgical Plan System in the subsequent 130 patients. Results: Brain tumors were diagnosed pathologically in 475 patients (86.4%), inflammatory process in 44 (8.0%), other lesions in 12 (2.2%) and no conclusive diagnosis was found in 19 (3.4%). The overall positive rate of biopsy was 96.6%, and the positive rate for brain tumor was 86.4%. Intracranial hematomas after biopsy were found in 13 cases (2.4%). Seizures occurred during the operation in 7 cases (1.2%), and slight and transient neurological deficits were found in 23 cases (4.2%). There were no deaths or other serious complications. Conclusions: The results suggest that the stereotactic biopsy is a reliable method to obtain histopathological diagnosis of intracranial mass lesions, and it is also of great help in selecting the appropriate management.
© 2001 S. Karger AG, Basel
- Alesch F, Pappaterra J, Trattnig S, et al: The role of stereotactic biopsy in radiosurgery. Acta Neurochir Suppl (Wien) 1995;63:20–24.
- Revesz T, Scaravilli F, Coutinho L, et al: Reliability of histological diagnosis including grading in gliomas biopsied by image-guided stereotactic technique. Brain 1993;116:781–793.
- Giunta F, Grasso G, Marini G, et al: Brain stem expanding lesions: stereotactic diagnosis and therapeutical approach. Acta Neurochir Suppl (Wien) 1989;46:86–89.
- Munari C, Rosler J, Musolino A, et al: Differential diagnosis between tumorous and non-tumorous intracranial lesions in children; a stereotactic approach. Acta Neurochir Suppl (Wien) 1989;46:75–78.
- Edner G: Stereotactic biopsy of intracranial space occupying lesions. Acta Neurochir (Wien) 1981;57:213–234.
- Bernstein M, Parrent AG: Complications of CT-guided stereotactic biopsy of intra-axial brain lesions. J Neurosurg 1994;81:165–168.
- Zamorano L, Katanick D, Dujovny M, et al: Tumor recurrence vs radionecrosis: an indication for multitrajectory serial stereotactic biopsies. Acta Neurochir Suppl (Wien) 1989;46:90–93.
- Lunsford LD, Somaza S, Kondziolka D, et al: Survival after stereotactic biopsy and irradiation of cerebral non-anaplastic, non-pilocytic astrocytoma. J Neurosurg 1995;82:523–529.
- Kelly PJ: Computer assisted stereotactic biopsy and volumetric resection of pediatric brain tumors. Neurol Clin 1991;9:317–336.
- Apuzzo MLJ, Sabshin JK: Computed tomographic guidance stereotactic in the management of intracranial mass lesions. Neurosurgery 1983;12:277–285.
- Yamasaki T, Moritake K, Takaya M, et al: Intraoperative use of Doppler ultrasound and endoscopic monitoring in the stereotactic biopsy of malignant brain tumors. J Neurosurg 1994;80:570–574.
- Gilsbach JM, Hassler WE: Introperative Doppler and real time sonography in neurosurgery. Neurosurg Rev 1984;7:199–208.
- Michiesl J, Bosmans H, Nuttin B, et al: The use of magnetic resonance angiography in stereotactic neurosurgery. J Neurosurg 1995;82:982–987.
- Mundinger F, Ostertag CB, Birg W, Weigel K: Stereotactic treatment of brain lesions: Biopsy, interstitial radiotherapy (iridium-192 and iodine-125) and drainage procedures. Appl Neurophysiol 1980;43:198–203.
Article / Publication Details
Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.