Respiration
Case Report
An Elderly Patient with Hemophagocytic Syndrome due to Severe Mycoplasma Pneumonia with Marked HypercytokinemiaMizukane R.a · Kadota J.-i.b · Yamaguchi T.a · Kiya T.a · Fukushima H.a · Nakatomi M.a · Kohno S.baDepartment of Internal Medicine, National Nagasaki Hospital and bSecond Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan
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Article / Publication Details
Published online: February 08, 2002
Issue release date: January – February
Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 0
ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)
For additional information: https://www.karger.com/RES
Abstract
We present an extremely rare case of hemophagocytic syndrome (HPS) induced by fulminant Mycoplasma pneumoniae(Mp) pneumonia in an elderly adult. Erythrocytopenia and thrombocytopenia were observed in a patient with acute respiratory failure, liver dysfunction and renal failure. Mp-associated HPS was diagnosed in this case by clinical and laboratory findings, including a bone marrow aspiration specimen and serum Mp antibody titer. High serum levels of soluble interleukin-2 receptor, interleukin-6, human interleukin-10 and macrophage-colony stimulating factor were observed. Hypercytokinemia is a useful marker of disease activity and prognosis. Combined treatment with methylprednisolone and erythromycin was successful and led to a favorable outcome. Physicians should be aware of HPS as a complication in Mp infection.
© 2002 S. Karger AG, Basel
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Article / Publication Details
Published online: February 08, 2002
Issue release date: January – February
Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 0
ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)
For additional information: https://www.karger.com/RES
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