Blood Purification

Research Article

Effects of Peritoneal Dialysis on Clinical Factors and Functional Performance

Chang W.a · Liu Y.a · Cheng B.-C.b · Zhang W.a · Wu C.-H.b · Wang X.a · Han Y.a · Tu Y.a · Chen J.-B.b

Author affiliations

aDepartment of Nephrology, Tianjin First Center Hospital, Tianjin, China
bDivision of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan

Keywords: Peritoneal dialysisAgeKarnofsky performance status scaleFunctional performanceSexAlbuminDiabetes

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Blood Purif 2019;48:124–130
https://doi.org/10.1159/000496081

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Article / Publication Details

First-Page Preview
Abstract of Research Article

Received: June 28, 2018
Accepted: December 07, 2018
Published online: January 30, 2019
Issue release date: August 2019

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 3

ISSN: 0253-5068 (Print)
eISSN: 1421-9735 (Online)

For additional information: https://www.karger.com/BPU

Abstract

Background: We investigated the longitudinal trend of functional performance in peritoneal dialysis (PD) patients over 1 year after PD commencement and its related clinical parameters. Methods: One hundred and ninety-six PD patients were enrolled in this study. Karnofsky Performance Status Scale(KPSS) scores were used to assess functional performance. Patients were stratified into 3 groups according to the changes in KPSS from baseline to 1 year. A logistic regression analysis was performed to examine the associations of clinical parameters with KPSS changes. Results: Patients with KPSS declined showed older age and higher serum albumin concentration reduction within 1 year than those in KPSS improved and stable changes. Age was the significant risk factor for KPSS decline, while male and diabetes were significantly associated with non-declined KPSS by multivariable logistic regression analysis. Conclusion: The main determinants of KPSS trend were age, sex, and diabetes in new PD patients.

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References

  1. Walker SR, Brar R, Eng F, Komenda P, Rigatto C, Prasad B, Bohm CJ, Storsley LJ, Tangri N: Frailty and physical function in chronic kidney disease: the CanFIT study. Can J Kidney Health Dis 2015; 2: 32.
  2. Ulutas O, Farragher J, Chiu E, Cook WL, Jassal SV: Functional disability in older adults maintained on peritoneal dialysis therapy. Perit Dial Int 2016; 36: 71–78.
  3. Cupisti A, D’Alessandro C, Finato V, Del Corso C, Catania B, Caselli GM, Egidi MF: Assessment of physical activity, capacity and nutritional status in elderly peritoneal dialysis patients. BMC Nephrol 2017; 18: 180.
  4. Johansen KL, Dalrymple LS, Delgado C, Chertow GM, Segal MR, Chiang J, Grimes B, Kaysen GA: Factors associated with frailty and its trajectory among patients on hemodialysis. Clin J Am Soc Nephrol 2017; 12: 1100–1108.
  5. Shimoda T, Matsuzawa R, Yoneki K, Harada M, Watanabe T, Matsumoto M, Yoshida A, Takeuchi Y, Matsunaga A: Changes in physical activity and risk of all-cause mortality in patients on maintence hemodialysis: a retrospective cohort study. BMC Nephrol 2017; 18: 154.
  6. Chen JB, Lam KK, Su YJ, Lee WC, Cheng BC, Kuo CC, Wu CH, Lin E, Wang YC, Chen TC, Liao SC: Relationship between Kt/V urea-based dialysis adequacy and nutritional status and their effect on the components of the quality of life in incident peritoneal dialysis patients. BMC Nephrol 2012; 13: 39.
  7. Merkus MP, Jager KJ, Dekker FW, De Haan RJ, Boeschoten EW, Krediet RT: Quality of life over time in dialysis: the Netherlands Cooperative Study on the Adequacy of Dialysis. NECOSAD Study Group. Kidney Int 1999; 56: 720–728.
  8. Modesto AP, Usvyat L, Calice-Silva V, Spigolon DN, Figueiredo AE, de Moraes TP, Olandoski M, Shimakura SE, Barreti P, Kotanko P, Pecoits-Filho R: Impact of the Karnofsky performance status on survival and its dynamics during the terminal year of peritoneal dialysis patients. Perit Dial Int 2018; 38: 24–29.
  9. Ng JK, Kwan BC, Chow KM, Cheng PM, Law MC, Pang WF, Leung CB, Li PK, Szeto CC: Frailty in Chinese peritoneal dialysis patients: prevalence and prognostic significance. Kidney Blood Press Res 2016; 41: 736–745.
  10. Mor V, Laliberte L, Morris JN, Wiemann M: The karnofsky performance status scale. An examination of its reliability and validity in a research setting. Cancer 1984; 53: 2002–2007.
  11. Ifudu O, Paul HR, Homel P, Friedman EA: Predictive value of functional status for mortality in patients on maintenance hemodialysis. Am J Nephrol 1998; 18: 109–116.
  12. Arogundade FA, Zayed B, Daba M, Barsoum RS: Correlation between Karnofsky performance status scale and short-form health survey in patients on maintenance hemodialysis. J Natl Med Assoc 2004; 96: 1661–1667.
  13. McClellan WM, Anson C, Birkeli K, Tuttle E: Functional status and quality of life: predictors of early mortality among patients entering treatment for end stage renal disease. J Clin Epidemiol 1991; 44: 83–89.
  14. Taskapan H, Baysal O, Karahan D, Durmus B, Altay Z, Ulutas O: Vitamin D and muscle strength, functional ability and balance in peritoneal dialysis patients with vitamin D deficiency. Clin Nephrol 2011; 76: 110–116.
  15. Cobo G, Gallar P, Gama-Axelsson T, Di Gioia C, Qureshi AR, Camacho R, Vigil A, Heimburger O, Ortega O, Rodriguez I, Herrero JC, Barany P, Lindholm B, Stenvinkel P, Carrero JJ: Clinical determinants of reduced physical activity in hemodialysis and peritoneal dialysis patients. J Nephrol 2015; 28: 503–510.
  16. Du Bois D, Du Bois EF: A formula to estimate the approximate surface area if height and weight be known. 1916. Nutrition 1989; 5: 303–311; discussion 312–303.
  17. Lai YC, Wang CY, Moi SH, Wu CH, Yang CH, Chen JB: Factors associated with functional performance among patients on hemodialysis in Taiwan. Blood Purif 2018; 46: 12–18.
  18. Johansen KL, Kaysen GA, Dalrymple LS, Grimes BA, Glidden DV, Anand S, Chertow GM: Association of physical activity with survival among ambulatory patients on dialysis: the comprehensive dialysis study. Clin J Am Soc Nephrol 2013; 8: 248–253.
  19. Chen JB, Lee WC, Cheng BC, Moi SH, Yang CH, Lin YD: Impact of risk factors on functional status in maintenance hemodialysis patients. Eur J Med Res 2017; 22: 54.
  20. Painter PL, Agarwal A, Drummond M: Physical function and physical activity in peritoneal dialysis patients. Perit Dial Int 2017; 37: 598–604.
  21. Oishi D, Koitabashi K, Hiraki K, Imai N, Sakurada T, Konno Y, Shibagaki Y, Yasuda T, Kimura K: Physical activity is associated with serum albumin in peritoneal dialysis patients. Adv Perit Dial 2012; 28: 148–152.

Article / Publication Details

First-Page Preview
Abstract of Research Article

Received: June 28, 2018
Accepted: December 07, 2018
Published online: January 30, 2019
Issue release date: August 2019

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 3

ISSN: 0253-5068 (Print)
eISSN: 1421-9735 (Online)

For additional information: https://www.karger.com/BPU

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2019, Vol.48, No. 2

August 2019

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