European Surgical Research
Original Paper
The Value of Pre-Emptive Analgesia in the Treatment of Postoperative Pain after Laparoscopic CholecystectomyUzunköy A. · Coskun A. · Akinci O.F.Harran University School of Medicine, Department of Surgery, Sanliurfa, Turkey
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Article / Publication Details
Published online: May 02, 2001
Issue release date: January – February
Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 2
ISSN: 0014-312X (Print)
eISSN: 1421-9921 (Online)
For additional information: https://www.karger.com/ESR
Abstract
Background and Aim: Postoperative pain is an important surgical problem. Recent studies in pain pathophysiology have led to the hypothesis that with pre-operative administration of analgesics (pre-emptive analgesia) it may be possible to prevent or reduce postoperative pain. This study was planned to investigate the efficacy of pre-emptive analgesia on postoperative pain after laparoscopic cholecystectomy. Methods: 45 patients undergoing laparoscopic cholecystectomy were randomized into three groups. Bupivacaine was injected into the area of skin incision before trocar entry and after trocar removal in group 1 and 2, respectively; however, this procedure was not applied to the control group. The pain score of the patients was evaluated by the visual analogue scale (VAS) at 1, 4, 12and 24 h after surgery. The daily analgesic requirement was evaluated in terms of diclophenac sodium (Diclomec, Abdi Ibrahim, 75 mg) intake/day. Analgesics were given to the patients whose VAS was 5 or higher. Results: While there was no significant difference in VAS scores between group 1 and 2, the mean pain scores of these two groups were found to be significantly lower than of the control group although the analgesic requirement of the patients in each group was not statistically significant. Conclusion: Pre-emptive analgesia is as effective as postsurgical local anaesthesia in reducing postoperative pain.
© 2001 S. Karger AG, Basel
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References
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Unver S, Unlu S, Ozgok A, et al: Preemptive analgesia in abdominal surgery: Combination of Meperedine, Ketorolac and 5% Bupivacaine infiltration. Türk Anesteziyol Reanimasyon Cemiyeti Mecumasi 1997;25:456–460.
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External Resources
- Dahl JB, Kehlet H: The value of preemptive analgesia in the treatment of postoperative pain. Br J Anaesth 1993;70:434–439.
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Ready LB: Acute postoperative pain; in Miller R (ed): Anaesthesia, ed 4. New York, Churchill Livingstone, 1994, pp 2327–2334.
Article / Publication Details
Published online: May 02, 2001
Issue release date: January – February
Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 2
ISSN: 0014-312X (Print)
eISSN: 1421-9921 (Online)
For additional information: https://www.karger.com/ESR
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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