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Original Paper

Influence of Preeclampsia or Maternal Intake of Omega–3 Fatty Acids on the Vasoactive Effect of Prostaglandin F-Two-Alpha in Human Umbilical Arteries

Haugen G.a · Helland I.b

Author affiliations

Departments of aObstetrics and Gynecology and bPediatric Research, National Hospital, University of Oslo, Norway

Related Articles for ""

Gynecol Obstet Invest 2001;52:75–81

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: September 28, 2001
Issue release date: September 2001

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 2

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: https://www.karger.com/GOI

Abstract

The vasoactive effect of prostaglandin F (PGF) was studied in in vitro perfused human umbilical arteries following maternal dietary supplementation with ω–3 fatty acids or in pregnancies complicated by a moderate degree of preeclampsia. In most preparations PGF induced a biphasic pressure response with a transient dilatation followed by a constrictory response. The pressure increase was significant in both groups, but no significant differences in the constrictory response or in the proportions of preparations displaying dilatatory responses were observed when compared to appropriate control groups. In conclusion, neither preeclampsia nor dietary supplementation with cod-liver oil had any significant effect on the vasoactive response to PGF in umbilical cord arteries.

© 2001 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: September 28, 2001
Issue release date: September 2001

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 2

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: https://www.karger.com/GOI


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