Cardiology

General Cardiology

Left Ventricular Hypertrophy and Diastolic Dysfunction in Healthy Pregnant Women

Schannwell C.M.a · Zimmermann T.b · Schneppenheim M.a · Plehn G.a · Marx R.a · Strauer B.E.a

Author affiliations

aClinic of Cardiology, Pneumology and Angiology, and bClinic of Gynecology and Obstetrics, Heinrich Heine University Düsseldorf, Germany

Keywords: Diastolic dysfunctionHemodynamic parametersLeft ventricular hypertrophyLeft ventricular systolic functionNatural volume overloadPregnancy

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Cardiology 2002;97:73–78
https://doi.org/10.1159/000057675

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Article / Publication Details

First-Page Preview
Abstract of General Cardiology

Published online: April 25, 2002
Issue release date: April 2002

Number of Print Pages: 6
Number of Figures: 2
Number of Tables: 3

ISSN: 0008-6312 (Print)
eISSN: 1421-9751 (Online)

For additional information: https://www.karger.com/CRD

Abstract

Objective: The purpose of this study was to examine which hemodynamic parameters change under the natural volume overload of pregnancy. Study Design: 46 healthy pregnant women were echocardiographically examined during the course of pregnancy. To evaluate left ventricular diastolic function, mitral inflow and pulmonary venous flow profiles were used. Fractional shortening and left ventricular muscle mass were calculated. Results: In the course of pregnancy the left ventricular muscle mass index increased (from 66 ± 6 to 96 ± 9 g/m2), fractional shortening decreased (from 38 ± 4 to 32 ± 6%) and a disturbed diastolic relaxation pattern was documented. Eight weeks after delivery, all left ventricular systolic and diastolic functional parameters returned to normal values. Conclusion: The natural volume overload in pregnancy leads to a reversible ‘physiological’ left ventricular hypertrophy, a short-term decrease in systolic function and a significant change in left ventricular diastolic function.

© 2002 S. Karger AG, Basel



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Article / Publication Details

First-Page Preview
Abstract of General Cardiology

Published online: April 25, 2002
Issue release date: April 2002

Number of Print Pages: 6
Number of Figures: 2
Number of Tables: 3

ISSN: 0008-6312 (Print)
eISSN: 1421-9751 (Online)

For additional information: https://www.karger.com/CRD

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2002, Vol.97, No. 2

April 2002

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