Cyclosporin A Treatment for Membranoproliferative Glomerulonephritis Type IIKiyomasu T.a · Shibata M.a · Kurosu H.a · Shiraishi K.a · Hashimoto H.a · Hayashidera T.a · Akiyama Y.a · Takeda N.b
Departments of Pediatrics,aKyoto National Hospital, Kyoto, and bKurashiki Central Hospital, Okayama, Japan
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A nephrotic patient with membranoproliferative glomerulonephritis type II (MPGN II) was treated with cyclosporin A (CSA) and alternate-day low-dose prednisolone. This patient developed the nephrotic syndrome twice. The second episode of the nephrotic syndrome was steroid resistant, and therefore this patient was treated with a CSA regimen. During treatments with alternate-day low-dose prednisolone and CSA, this patient recovered from the nephrotic syndrome. We conclude that CSA therapy may be effective for patients with the steroid-resistant nephrotic syndrome caused by MPGN II.
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