Gerontology

Clinical Section

Evaluation of Gastric Motor Activity in the Elderly by Electrogastrography and the 13C-Acetate Breath Test

Shimamoto C. · Hirata I. · Hiraike Y. · Takeuchi N. · Nomura T. · Katsu K.-i.

Author affiliations

Division of Gastroenterology, Department of Internal Medicine II, Osaka Medical College, Osaka, Japan

Keywords: Gastric motilityGastric emptyingElectrogastrography13C-acetate breath testElderly

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Gerontology 2002;48:381–386
https://doi.org/10.1159/000065500

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Article / Publication Details

First-Page Preview
Abstract of Clinical Section

Received: July 23, 2001
Accepted: November 21, 2001
Published online: October 18, 2002
Issue release date: November – December

Number of Print Pages: 6
Number of Figures: 4
Number of Tables: 0

ISSN: 0304-324X (Print)
eISSN: 1423-0003 (Online)

For additional information: https://www.karger.com/GER

Abstract

Background: Elderly people frequently have symptoms of fullness and appetite loss due to impaired gastric motor activity. These symptoms may cause malnutrition, immunosuppression and other complications. Objective: The effects of aging and daily activity on gastric motility in the elderly were investigated by electrogastrography and the 13C-acetate breath test. Methods: We enrolled seven active elderly subjects (active elderly group), seven elderly subjects staying at a geriatric facility who had reduced mental and physical capacities (inactive elderly group) and seven healthy young volunteers (young group). Electrogastrography was recorded before and after ingestion of a 13C-acetate-mixed liquid meal. Expired air was sampled every 10 min after the meal to measure the 13CO2 concentration. Results: The ratio of the incidence of the 3-cpm wave (gastric intrinsic frequency) during the postprandial period compared to the fasting state was reduced in both elderly groups compared to young subjects, and the reduction was greater in the inactive elderly than in the active elderly group. The ratio of the amplitude of the peak frequency during the postprandial period to that in the fasting state (power ratio) was also lower in the elderly groups. The time of peak 13CO2 expiration was delayed in the active elderly and more so in the inactive elderly group. Conclusion: Postprandial peristalsis and gastric contractile force are reduced in the elderly, and gastric emptying is delayed indicating a reduction in gastric motor activity.

© 2002 S. Karger AG, Basel



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Article / Publication Details

First-Page Preview
Abstract of Clinical Section

Received: July 23, 2001
Accepted: November 21, 2001
Published online: October 18, 2002
Issue release date: November – December

Number of Print Pages: 6
Number of Figures: 4
Number of Tables: 0

ISSN: 0304-324X (Print)
eISSN: 1423-0003 (Online)

For additional information: https://www.karger.com/GER

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2002, Vol.48, No. 6

November – December

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