European Urology

Stones

Effects of a ‘Common Sense Diet’ on Urinary Composition and Supersaturation in Patients with Idiopathic Calcium Urolithiasis

Hess B.b · Mauron H.a · Ackermann D.c · Jaeger P.a

Author affiliations

aPoliclinic and bDepartment of Internal Medicine, University Hospital, Bern, and cDepartment of Urology, Kantonsspital, St. Gallen, Switzerland

Keywords: Dietary adviceFluid intakeHypercalciuriaHyperoxaluriaIdiopathic calcium urolithiasisProtein intakeUrinary supersaturation measurementsUrine volume

Related Articles for ""
Eur Urol 1999;36:136–143
https://doi.org/10.1159/000067985

Log in to MyKarger to check if you already have access to this content.




Forgot your password
Sign up to MyKarger

Buy

  • FullText & PDF
  • Unlimited re-access via MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more
CHF 38.00 *
EUR 35.00 *
USD 39.00 *

Select

KAB

Buy a Karger Article Bundle (KAB) and profit from a discount!


If you would like to redeem your KAB credit, please log in.

Save over 20% compared to the individual article price.

Learn more

Rent/Cloud

  • Rent for 48h to view
  • Buy Cloud Access for unlimited viewing via different devices
  • Synchronizing in the ReadCube Cloud
  • Printing and saving restrictions apply
Rental: USD 8.50
Cloud: USD 20.00

Select

Subscribe

For eJournal Archive and eJournal Backfiles information please contact Karger service

* The final prices may differ from the prices shown due to specifics of VAT rules.

Article / Publication Details

First-Page Preview
Abstract of Stones

Published online: July 08, 1999
Issue release date: August 1999

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 4

ISSN: 0302-2838 (Print)
eISSN: 1873-7560 (Online)

For additional information: https://www.karger.com/EUR

Abstract

Objectives: To test whether dietary advice as the only treatment is able to reduce urinary supersaturation in patients with idiopathic calcium urolithiasis. Methods: By means of EQUIL 2, we calculated relative supersaturations of calcium oxalate (RSCaOx), brushite (RSBrushite), apatite (RSApatite) and uric acid (RSUA) of 24-hour urine samples of 68 healthy male controls as well as of 47 male idiopathic calcium stone formers (ICSF) before and after individualized dietary advice (DA). Main goals of DA were (1) to keep urine volume > 2,000 ml/day, and (2) to reduce meat protein intake to 1 g/kg body weight per day. Compliance was judged from changes in urine volume and UUrea×V. Results: In the whole group of ICSF, DA did not alter supersaturations. Only in those 9 ICSF (19%) with good compliance (increase in volume and decrease in UUrea×V), RSCaOx and RSUA fell by 26 and 49%, respectively. Besides poor compliance, these findings can be explained by positive correlations between changes in volume and UUrea×V in ICSF (r = 0.319, p = 0.037) or UNa×V (r = 0.342, p = 0.019). For instance, ICSF with volumes ≧ 2,000 ml/day had evidence of elevated protein and salt intake; thus, DA mainly focused on protein and salt intake, but not on volume. This resulted in decreases in UUrea×V and UNa×V, but also in volume; thus, RSCaOx remained unaltered. Conclusions: DA is able to significantly lower RSCaOx; however, because intakes of fluid and protein are directly and positively linked to each other, this only can be achieved if high fluid and lower meat protein intake are equally stressed in all ICSF.



Related Articles:

References

  1. Curhan GC, Willett WC, Rimm EB, Stampfer MJ: A prospective study of dietary calcium and other nutrients and the risk of symptomatic kidney stones. N Engl J Med 1993;328:833–838.
    External Resources
  2. Robertson WG: Diet and calcium stones. Miner Electrolyte Metab 1987;13:228–234.
    External Resources
  3. Goldfarb S: Dietary factors in the pathogenesis and prophylaxis of calcium nephrolithiasis. Kidney Int 1988;34:544–555.
    External Resources
  4. Hess B, Ackermann D, Essig M, Takkinen R, Jaeger Ph: Renal mass and serum calcitriol in male idiopathic calcium renal stone formers: Role of protein intake. J Clin Endocrinol Metab 1995;80:1916–1921.
    External Resources
  5. Robertson WG, Heyburn PJ, Peacock M, Hanes FA, Swaminathan R: The effect of high animal protein intake on the risk of calcium stone formation in the urinary tract. Clin Sci 1979;57:285–288.
    External Resources
  6. Grover PG, Ryall RL: Urate and calcium oxalate stones: From repute to rhetoric to reality. Miner Electrolyte Metab 1994;20:361–370.
    External Resources
  7. Kok DJ, Iestra JA, Doorenbos CJ, Papapoulos SE: The effects of dietary excesses in animal protein and in sodium on the composition and the crystallization kinetics of calcium oxalate monohydrate in urines of healthy men. J Clin Endocrinol Metab 1990;71:861–867.
    External Resources
  8. Robertson WG, Peacock M: The cause of idiopathic calcium stone disease: Hypercalciuria or hyperoxaluria? Nephron 1980;26:105–110.
    External Resources
  9. Ettinger B: Recurrent nephrolithiasis: Natural history and effect of phosphate therapy, a double-blind controlled study. Am J Med 1976;61:200–206.
    External Resources
  10. Brocks P, Dahl C, Wolf H: Do thiazides prevent recurrent idiopathic renal calcium stones? Lancet 1981;ii:124–125.
  11. Rao PN, Prendiville V, Buxton A, Moss DG, Blacklock NJ: Dietary management of urinary risk factors in renal stone formers. Br J Urol 1982;54:578–583.
    External Resources
  12. Iguchi M, Umekawa T, Ishikawa Y, Katayama Y, Kodama M, Takada M, Katoh Y, Kataoka K, Kohri K, Kurita T: Clinical effects of prophylactic dietary treatment on renal stones. J Urol 1990;144:229–232.
    External Resources
  13. Hesse A, Siener R, Heynck H, Jahnen A: The influence of dietary factors on the risk of urinary stone formation. Scanning Microsc 1993;7:1119–1128.
    External Resources
  14. Hess B: ‘Bad dietary habits’ and recurrent calcium oxalate nephrolithiasis. Nephrol Dial Transplant 1998;13:1033–1038.
    External Resources
  15. Mitch WE, Walser M: Nutritional therapy of the uremic patient; in Brenner BM, Rector FC Jr (eds): The Kidney, ed 3. Philadelphia, Saunders, 1986, vol II, pp 1759–1790.
  16. Oh MS: A new method for estimating G-I absorption of alkali. Kidney Int 1989;36:915–917.
    External Resources
  17. Hess B: Nierensteine; in Colombo JP (ed): Klinisch-chemische Urindiagnostik. Rotkreuz (Switzerland), Labolife Verlagsgemeinschaft, 1994, pp 283–294.
  18. Chiriboga J: Some properties of an oxalic oxidase purified from barley seedlings. Biochem Biophys Res Commun 1963;11:277–282.
  19. Toftegaard Nielsen T: A method for enzymatic determination of citrate in serum and urine. Scand J Clin Lab Invest 1976;36:513–519.
    External Resources
  20. Bucholz AE, Verplough CI, Smith JL: A method for the simultaneous measurement of chloride, nitrate, and sulfate in aqueous samples by nonsuppressed ion chromatography. J Chromatogr Sci 1982;20:449–501.
    External Resources
  21. Hess B, Michel R, Takkinen R, Ackermann D, Jaeger Ph: Risk factors for low urinary citrate in calcium nephrolithiasis: Low vegetable fibre intake and low urine volume to be added to the list. Nephrol Dial Transplant 1994;9:642–649.
    External Resources
  22. Werness PG, Brown CM, Smith LH, Finlayson B: EQUIL 2: A basic computer program for the calculation of urinary saturation. J Urol 1985;134:1242–1244.
    External Resources
  23. Sachs L: Angewandte Statistik, ed 7. Berlin, Springer, 1992, pp 553–556.
  24. Tiselius HG: Aspects on estimation of the risk of calcium oxalate crystallization in urine. Urol Int 1991;47:255–259.
    External Resources
  25. Robertson GL, Berl T: Pathophysiology of water metabolism; in Brenner BM (ed): The Kidney, ed 5. Philadelphia, Saunders, 1996, vol I, pp 873–928.
  26. McCormack M, Dessureault J, Guitard M: The urine-specific gravity dipstick: A useful tool to increase fluid intake in stone-forming patients. J Urol 1991;146:1475–1477.
    External Resources

Article / Publication Details

First-Page Preview
Abstract of Stones

Published online: July 08, 1999
Issue release date: August 1999

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 4

ISSN: 0302-2838 (Print)
eISSN: 1873-7560 (Online)

For additional information: https://www.karger.com/EUR

Copyright / Drug Dosage / Disclaimer

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

Article Tools
Article Details

1999, Vol.36, No. 2

August 1999

Article

Recommend This
TOP