Brain, Behavior and Evolution
Original Paper
The Scaling of White Matter to Gray Matter in Cerebellum and NeocortexBush E.C. · Allman J.M.Biology Division, California Institute of Technology, MC 216-76, Pasadena, Calif., USA
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Article / Publication Details
Received: October 03, 2002
Accepted: November 26, 2002
Published online: March 13, 2003
Issue release date: February 2003
Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 2
ISSN: 0006-8977 (Print)
eISSN: 1421-9743 (Online)
For additional information: https://www.karger.com/BBE
Abstract
It is known that the white matter of neocortex increases disproportionately with brain size. However, relatively few measurements have been made of white matter/gray matter scaling in the cerebellum. We present data on the volumes of white and gray matter in both structures, taken from 45 species of mammals. We find a scaling exponent of 1.13 for cerebellum and 1.28 for neocortex. The 95% confidence intervals for our estimates of these two exponents do not overlap. This difference likely reflects differences in the connectivity and/or micro-structure of white matter in the two regions.
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References
-
Allman, J. (1999) Evolving Brains. Scientific American Books, New York.
- Andersen, B., L. Korbo, and B. Pakkenberg (1992) A quantitative study of the human cerebellum with unbiased stereological techniques. J. Comp. Neurol., 326: 549–560.
- Braitenberg, V., D. Heck, and F. Sultan (1997) The detection and generation of sequences as a key to cerebellar function: Experiments and theory. Behav. Brain Sci., 20: 229–77.
- Campos, G., and W. Welker (1976) Comparisons between brains of a large and a small hystricomorph rodent – capybara, Hydrochoerus and guinea-pig, Cavia – neocortical projection regions and measurements of brain subdivisions. Brain Behav. Evol., 13: 243–266.
- Changizi, M. (2001) Principles underlying mammalian neocortical scaling. Biol. Cyber., 84:207–215.
-
Frahm, H. D., H. Stephan, and M. Stephan (1982) Comparison of brain structure volumes in Insectivora and Primates. I. neocortex. J. Hirnforsch., 23: 375–389.
- Gundersen, H., E. Jensen, K. Kieu, and J. Nielsen (1999) The efficiency of systematic sampling in stereology reconsidered. J. Microsc., 193: 199–211.
-
Jolicoeur, P. (1968) Interval estimation of the slope of the major axis of a bivariate normal distribution in the case of a small sample. Biometrics, 24: 679–682.
- Korbo, L., B. Andersen, O. Ladefoged, and A. Moller (1993) Total numbers of various cell types in rat cerebellar cortex estimated using an unbiased stereological method. Brain Res., 609:262–268.
-
Kretschmann, H. J., U. Tafesse, and A. Herrmann (1982) Different volume changes of cerebral cortex and white matter during histological preparation. Microsc. Acta, 86: 13–24.
- Olivares, R., J. Montiel, and F. Aboitiz (2001) Species differences and similarities in the fine structure of the mammalian corpus callosum. Brain Behav. Evol., 57: 98–105.
-
Ramon y Cajal, S. (1888) Estructura de los centros nerviosos de las aves. Rev. Trimestr. Histol. 1:1–10.
- Rilling, J. K., and T.R. Insel (1999) The primate neocortex in comparative perspective using magnetic resonance imaging. J. Hum. Evol. 37:191–223.
-
Schlenska, G. (1974) Volumen und Oberflächenmessungen an Gehirnen verschiedener Säugetiere im Vergleich zu einem errechneten Modell. J. Hirnforsch., 15: 401–408.
- Schuz, A., and H. Preissl (1996) Basic connectivity of the cerebral cortex and some considerations on the corpus callosum. Neurosci. Biobehav. Rev., 20: 567–570.
- Shinoda, Y., Y. Sugiuchi, T. Futami, and R. Izawa (1992) Axon collaterals of mossy fibers from the pontine nucleus in the cerebellar dentate nucleus. J. Neurophysiol. 67: 547–560.
-
Stephan, H., G. Baron, and H. Frahm (1991) Insectivora. Springer-Verlag, New York.
-
Sultan, F. (2002) Brain evolution – analysis of mammalian brain architecture. Nature, 415:133–134.
- Wu, H., I. Sugihara, and Y. Shinoda (1999) Projection patterns of single mossy fibers originating from the lateral reticular nucleus in the rat cerebellar cortex and nuclei. J. Comp. Neurol., 411:97–118.
- Zhang, K., and T. Sejnowski (2000) A universal scaling law between gray matter and white matter of cerebral cortex. Proc. Nat. Acad. Sci. (USA) 97: 5621–5626.
Article / Publication Details
Received: October 03, 2002
Accepted: November 26, 2002
Published online: March 13, 2003
Issue release date: February 2003
Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 2
ISSN: 0006-8977 (Print)
eISSN: 1421-9743 (Online)
For additional information: https://www.karger.com/BBE
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