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Original Paper

Spontaneous Resolution of Calvarial Eosinophilic Granuloma in Children

Oliveira M.a,c · Steinbok P.a,c · Wu J.b,d · Heran N.a,c · Cochrane D.a,c

Author affiliations

Divisions of aPediatric Neurosurgery and bOncology, British Columbia’s Children’s Hospital, Children and Women’s Health Centre, Departments of cSurgery and dPediatrics, University of British Columbia, Vancouver, B.C., Canada

Related Articles for ""

Pediatr Neurosurg 2003;38:247–252

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: September 20, 2002
Accepted: January 21, 2003
Published online: April 16, 2003
Issue release date: May 2003

Number of Print Pages: 6
Number of Figures: 4
Number of Tables: 0

ISSN: 1016-2291 (Print)
eISSN: 1423-0305 (Online)

For additional information: https://www.karger.com/PNE

Abstract

Objective: The recommended treatment for solitary calvarial eosinophilic granuloma (EG) is surgical resection by curettage, craniectomy or craniotomy. The purpose of this study was to describe the spontaneous resolution of calvarial EG and discuss ‘observation only’ as an option in the management of this condition. Methods: A retrospective review was performed of children with calvarial EG seen at a tertiary care children’s hospital. Of a total of 17 such patients, four were managed without any intervention and formed the basis of this report. Results: In all four patients treated by ‘observation only’, there was a tender calvarial mass which enlarged rapidly over a few days and then resolved slowly over many weeks. The diagnosis of EG was based on the findings of plain radiographs and/or computed tomography. All masses had resolved by 8 weeks, and the underlying cranial defect filled in spontaneously in all cases. There was no recurrence at follow-up, which ranged from 2 months to 7 years. Conclusions: ‘Observation only’ should be considered as a viable option in the management of children with solitary calvarial masses that have the radiographic features of EG. Consideration should be given to delaying surgical intervention to allow time to see if spontaneous resolution occurs.

© 2003 S. Karger AG, Basel


References

  1. Rawlings CE 3rd, Wilkins RH: Solitary eosinophilic granuloma of the skull. Neurosurgery 1984;15:155–161.
  2. Slater JM, Swarm OJ: Eosinophilic granuloma of bone. Med Pediatr Oncol 1980;8:151–164.
  3. Arseni C, Danaila L, Constantinescu A: Cranial eosinophilic granuloma. Neurochirurgia (Stuttg) 1977;20:189–199.
  4. Manaka S, Izawa M, Nawata H: Skull tumor simulating sinus pericranii. Case report. J Neurosurg 1977;46:671–673.
  5. Feldman RB, Moore DM, Hood CI, Hiles DA, Romano PE: Solitary eosinophilic granuloma of the lateral orbital wall. Am J Ophthalmol 1985;100:318–323.
  6. Shelby JH, Sweet RM: Eosinophilic granuloma of the temporal bone: Medical and surgical management in the pediatric patient. South Med J 1983;76:65–70.
  7. Appling D, Jenkins HA, Patton GA: Eosinophilic granuloma in the temporal bone and skull. Otolaryngol Head Neck Surg 1983;91:358–365.
  8. Martinez-Lage JF, Poza M, Cartagena J, Vicente JP, Biec F, de las Heras M: Solitary eosinophilic granuloma of the pediatric skull and spine. The role of surgery. Childs Nerv Syst 1991;7:448–451.
  9. Mitnick JS, Pinto RS: Computed tomography in the diagnosis of eosinophilic granuloma. J Comput Assist Tomogr 1980;4:791–793.
  10. Hadjigeorgi C, Parpounas C, Zarmakoupis P, Lafoyianni S: Eosinophilic granuloma of the temporal bone: Radiological approach in the pediatric patient. Pediatr Radiol 1990;20:546–549.
  11. Hermans R, De Foer B, Smet MH, Leysen J, Feenstra L, Fossion E, Baert AL: Eosinophilic granuloma of the head and neck: CT and MRI features in three cases. Pediatr Radiol 1994;24:33–36.
  12. David R, Oria RA, Kumar R, Singleton EB, Lindell MM, Shirkhoda A, Madewell JE: Radiologic features of eosinophilic granuloma of bone. AJR Am J Roentgenol 1989;153:1021–1026.
  13. Yanagawa T, Watanabe H, Shinozaki T, Ahmed AR, Shirakura K, Takagishi K: The natural history of disappearing bone tumours and tumour-like conditions. Clin Radiol 2001;56:877–886.
  14. Hefti F, Jundt G: Langerhans cell histiocytosis (in German). Orthopäde 1995;24:73–81.
  15. Kamimura M, Kinoshita T, Itoh H, Yuzawa Y, Takahashi J, Ohtsuka K: Eosinophilic granuloma of the spine: Early spontaneous disappearance of tumor detected on magnetic resonance imaging. Case report. J Neurosurg 2000;93(2 suppl):312–316.
  16. Schmitz L, Favara BE: Nosology and pathology of Langerhans cell histiocytosis. Hematol Oncol Clin North Am 1998;12:221–246.
  17. Herzog KM, Tubbs RR: Langerhans cell histiocytosis. Adv Anat Pathol 1998;5:347–358.
  18. Lavin PT, Osband ME: Evaluating the role of therapy in histiocytosis-X. Clinical studies, staging, and scoring. Hematol Oncol Clin North Am 1987;1:35–47.
  19. Leikin SL: Immunobiology of histiocytosis-X. Hematol Oncol Clin North Am 1987;1:49–61.
  20. Alvarez-Sala R, Prados C, de Miguel E, Garcia-Talavera I, Munoz J: Histiocytosis X and ankylosing spondylitis. A common pathogenesis? (in Spanish). An Med Interna 1996;13:339–340.
  21. Zeff RA, Freitag A, Grin CM, Grant-Kels JM: The immune response in halo nevi. J Am Acad Dermatol 1997;37:620–624.

Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: September 20, 2002
Accepted: January 21, 2003
Published online: April 16, 2003
Issue release date: May 2003

Number of Print Pages: 6
Number of Figures: 4
Number of Tables: 0

ISSN: 1016-2291 (Print)
eISSN: 1423-0305 (Online)

For additional information: https://www.karger.com/PNE


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