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Original Paper

The Five Symptom Dimensions and Depression in Schizophrenia

Lee K.-H.a,c · Harris A.W.b,d · Loughland C.M.a,c · Williams L.M.a,c

Author affiliations

aCognitive Neuroscience Unit, The Brain Dynamics Centre, bThe Brain Dynamics Centre, Westmead Hospital, cSchool of Psychology and dDepartment of Psychological Medicine, University of Sydney, Sydney, N.S.W., Australia

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Psychopathology 2003;36:226–233

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: February 11, 2003
Accepted: June 05, 2003
Published online: October 27, 2003
Issue release date: September – October

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 3

ISSN: 0254-4962 (Print)
eISSN: 1423-033X (Online)

For additional information: https://www.karger.com/PSP

Abstract

The aim of this study was to investigate the relationship between the five-factor model of psychopathology and depression in schizophrenia. Symptoms were rated using the Positive and Negative Syndrome Scale (PANSS) and the Montgomery and Åsberg Depression Rating Scale (MADRS) in 105 chronic patients with schizophrenia. Principal-component analysis (PCA) produced a five-factor solution for the PANSS (psychomotor poverty, disorganisation, reality distortion, excitement, and depression), and a two-factor solution for the MADRS (psychological and behavioural depression). The PANSS depression factor was highly associated with the MADRS psychological depression factor but not with MADRS behavioural depression. By contrast, the PANSS excitement factor showed a strong positive correlation with the behavioural depression factor but not with psychological depression. These MADRS factors were not associated significantly with the core PANSS factors, including psychomotor poverty. It is suggested that depression exists as an independent domain, differentiated from negative symptoms, in the structure of schizophrenia symptomatology.

© 2003 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: February 11, 2003
Accepted: June 05, 2003
Published online: October 27, 2003
Issue release date: September – October

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 3

ISSN: 0254-4962 (Print)
eISSN: 1423-033X (Online)

For additional information: https://www.karger.com/PSP


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