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Original Research Article

Getting Lost: Directed Attention and Executive Functions in Early Alzheimer’s Disease Patients

Chiu Y.-C.a · Algase D.b · Whall A.b · Liang J.c · Liu H.-C.d,e · Lin K.-N.d · Wang P.-N.d,e

Author affiliations

aChang-Gung University, Department and Graduate Institute of Nursing, Taoyuan, Taiwan; bUniversity of Michigan School of Nursing, and cUniversity of Michigan School of Public Health, Ann Arbor, Mich., USA; dNeurological Institute, Taipei Veterans General Hospital, and eDepartment of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan

Related Articles for ""

Dement Geriatr Cogn Disord 2004;17:174–180

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Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Received: July 17, 2003
Published online: March 17, 2004
Issue release date: March 2004

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 6

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM

Abstract

This study explores the link between directed attention (DA) and getting lost behavior (GLB) in early Alzheimer’s disease (AD) using a cross-sectional design with 3 groups. Based on their dementia levels, 116 community-dwelling participants were recruited from a teaching hospital in Taiwan and classified as the non-demented control, questionably demented, and mild AD groups. Statistical analyses include Pearson correlations, one-way ANOVA, and multiple regressions. Attentional impairments, consisting of distractibility, impulsivity, and executive function problems, significantly predict GLB in familiar and unfamiliar environments. Irritability and executive function problems are associated with mental difficulties in choosing a turn, whereas the use of way-finding strategies reduces GLB. Future interventions may include: (a) mental hygiene of aging; (b) programs targeted at improving attentional function and effective way-finding, and (c) inclusion of DA tests in a routine clinical neuropsychological examination for early detection and accurate diagnosis of dementia.

© 2004 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Received: July 17, 2003
Published online: March 17, 2004
Issue release date: March 2004

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 6

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM


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