The repair of γ-ray-induced chromosomal damage in human lymphocytes after exposure to extremely low frequency electromagnetic fieldsLloyd D.a · Hone P.a · Edwards A.a · Cox R.a · Halls J.b
aNational Radiological Protection Board, Chilton, Didcot, Oxon; bBrunel Institute for Bioengineering, Brunel University, Uxbridge (UK)
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G₀ human blood lymphocytes were irradiated with 2.0 Gy γ-rays and cultured to metaphase whilst held in a 50-Hz power frequency magnetic field of 0.23, 0.47 or 0.7 mT. No differences were found in the frequencies of γ-induced chromosome aberrations observed in cells held in the EM fields compared with replicates held in a sham coil. Similar field conditions have been reported to increase the frequency of γ-induced HPRT mutations, leading to a suggestion that the EM fields alter the fidelity of repair of genomic lesions. This was not confirmed by the chromosome aberration assay described here.
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