Blood Purification
Luncheon Seminar
Clinical Benefit of Preserving Residual Renal Function in Patients after Initiation of DialysisKuno T. · Matsumoto K.Second Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan
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Article / Publication Details
Published online: January 27, 2005
Issue release date: January 2005
Number of Print Pages: 5
Number of Figures: 4
Number of Tables: 1
ISSN: 0253-5068 (Print)
eISSN: 1421-9735 (Online)
For additional information: https://www.karger.com/BPU
Abstract
Preserving residual renal function (RRF) after initiation of dialysis therapy is desirable for improving quality of life in ESRD patients. It has been believed that RRF declines more slowly in patients receiving continuous ambulatory peritoneal dialysis (CAPD) than in patients treated with other forms of maintenance dialysis. Episodes of intravascular volume depletion might be expected to cause more rapid loss of RRF, and are more frequent in patients on hemodialysis, which is intermittent therapy. However, recently it was demonstrated that in hemodialysis using high-flux biocompatible membrane and ultrapure water, RRF declines at a rate indistinguishable from that in CAPD. The HDF using ultrapure dialysate and the substitution fluid may show to preserve RRF as well as CAPD patients. In future, it might be a major concern for the assessment of the HDF by a multicenter clinical study for preserving RRF.
© 2004 S. Karger AG, Basel
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References
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Rottembourg J, Issad B, Gallego JL, et al: Evolution of residual renal function in patients undergoing maintenance hemodialysis or continuous ambulatory peritoneal dialysis. Proc Eur Transplant Assoc 1982;19:397–403.
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Lysaght MJ, Vonesh EF, Gotch F, et al: The influence of dialysis treatment modality on the decline of remaining renal function. Trans Am Soc Artif Intern Organs 1991;37:598–604.
External Resources
- McKane W, Chandna SM, Tattersall JE, et al: Identical decline of residual renal function in high-flux biocompatible hemodialysis and CAPD. Kidney Int 2002;61:256–265.
- Teschan PE: Unperceived underdialysis. ASAIO J 2003;49:350–354.
- Bonomini V, Albertazzi A, Vangelista A, et al: Residual renal function and effective rehabilitation in chronic dialysis. Nephron 1976;16:89–99.
- Merkus MP, Jager KJ, Dekker FW, et al: Predictors of poor outcome in chronic dialysis patients; The Netherlands Cooperative Study on the adequacy of dialysis. Am J Kidney Dis 2000;35:69–79.
- Shemin D, Boston AG, Laliberty P, et al: Residual renal function and mortality risk in hemodialysis patients. Am J Kidney Dis 2001;38:85–90.
- Suda T, Hiroshige K, Ohta T, et al: The contribution of residual renal function to overall nutritional status in chronic hemodialysis patients. Nephrol Dial Transplant 2000;15:396–401.
- Caramelo C, Alcazar R, Gallar P, et al: Choice of dialysis membrane does not influence the outcome of residual renal function in haemodialysis patients. Nephrol Dial Transplant 1994;9:675–677.
- McCarthy JT, Jenson BM, Squillace DP, et al: Improved preservation of residual renal function in chronic hemodialysis patients using polysulfone dialyzers. Am J Kidney Dis 1997;29:576–583.
- Schiffl H, Lang SM, Fischer R: Ultrapure dialysis fluid slows loss of residual renal function in new dialysis patients. Nephrol Dial Transplant 2002;17:1814–1818.
Article / Publication Details
Published online: January 27, 2005
Issue release date: January 2005
Number of Print Pages: 5
Number of Figures: 4
Number of Tables: 1
ISSN: 0253-5068 (Print)
eISSN: 1421-9735 (Online)
For additional information: https://www.karger.com/BPU
Copyright / Drug Dosage / Disclaimer
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