Long-Term Remission of Idiopathic Cervical Dystonia after Treatment with Botulinum ToxinGiladi N.a · Meer J.b · Kidan H.b · Honigman S.b
aDepartment of Neurology, Sourasky Medical Center, Tel-Aviv University, Tel-Aviv, and bDepartment of Neurology, Carmel Medical Center, Haifa, Israel
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Botulinum toxin type A (BTX-A) treatment for cervical dystonia is traditionally considered a purely symptomatic treatment. BTX-A blocks acetyl choline exocytosis for 3–6 months and most patients require reinjection after this period. We report on 6 patients (mean age 41.6 years, range 18–69) with idiopathic cervical dystonia who were treated with BTX-A injections and became asymptomatic for 2–4 years. Four patients showed remission after the first BTX-A treatment, 1 patient after the second set of injections and 1 after the third session. Amelioration of neck dystonia was observed within 1–4 weeks after the last BTX-A treatment and all 6 patients are symptom-free, off antidystonic medications for over 2 years. The possibility that BTX-A treatment may increase the chances of development of clinical remission in patients with idiopathic cervical dystonia is discussed.
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