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Fluorescence Cystoscopy in the Management of Bladder Cancer: A Help for the Urologist!

Jichlinski P. · Leisinger H.-J.

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Department of Urology, CHUV, Lausanne, Switzerland

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Urol Int 2005;74:97–101

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Article / Publication Details

First-Page Preview
Abstract of Paper

Received: May 24, 2004
Accepted: June 08, 2004
Published online: March 07, 2005
Issue release date: March 2005

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0

ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)

For additional information: https://www.karger.com/UIN

Abstract

As a disease characterized by a nature polymorphic and fluctuant in its evolution, superficial transitional cell carcinoma of the bladder remains a perpetual therapeutic challenge, and raises a great interest in the development of new diagnostic and surveillance techniques. This paper reviews 10 years of experience of fluorescence cystoscopy, a simple technique perfectly adapted to the current endoscopic equipment. Its principle is to enhance the visual contrast between benign and malignant cells. Three photosensitizing agents are available, two prodrugs: δ-aminolevulinic acid or hexaminolevulinate, and a natural substance: hypericin. With a detection rate of over 90% for carcinoma in situ and a real potential for detecting small tumors overlooked by standard cystoscopy, fluorescence cystoscopy may be clearly recommended in clinical practice. This technique favors a standardization of superficial bladder cancer endoscopic management and is susceptible to have a real impact on the disease recurrence and progression rate.

© 2005 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Paper

Received: May 24, 2004
Accepted: June 08, 2004
Published online: March 07, 2005
Issue release date: March 2005

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0

ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)

For additional information: https://www.karger.com/UIN


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