Alcoholic Case of Central Pontine Myelinolysis with Mainly Cerebellar SignsOzgur-Ilhan I.a · Demirbas H.a · Yalcın G.A.a · Yucesan C.b · Dogan Y.B.a
Departments of aPsychiatry and bNeurology, Ankara University School of Medicine, Ankara, Turkey
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The etiology of central pontine myelinolysis (CPM) is usually related to rapid correction of hyponatremia and alcoholism. Here a case with CPM predominated by cerebellar signs is described, and the neuropsychological assessment of the case is presented as well. Blood biochemistry revealed a normal sodium level and neuropsychological examination revealed impairment in attention and concentration, reduced immediate memory span, and impaired delayed recall. Further studies are needed to discover whether these neuropsychological signs are specific for CPM or due to alcoholism in general.
© 2005 S. Karger AG, Basel
- Skullerud K, Andersen N, Lundevall J: Cerebral lesions and causes of death in male alcoholics. Int J Legal Med 1991;104:209–213.
- Pirzada NA, Ali II: Central pontine myelinolysis. Mayo Clin Proc 2001;76:559–562.
- Vermetten E, Rutten SJE, Boon PJ, Hofman PAM, Leentjens AFG: Neuropsychiatric and neuropsychological manifestations of central pontine myelinolysis. Gen Hosp Psychiatry 1999;21:296–302.
Kom-Lubetzki I, Virozub Y, Orbach H: Central pontine myelinolysis after alcohol withdrawal. Isr Med Assoc J 2002;4:656.
- Garzon T, Mellibovsky L, Roquer J, Perich X, Diez-Perez A: Ataxic form of central pontine myelinolysis. Lancet Neurol 2002;1:517–518.
- Seiser A, Schwarz S, Aichinger-Steiner MM, Funk G, Schnider P, Brainin M: Parkinsonism and dystonia and central pontine and extrapontine myelinolysis. J Neurol Neurosurg Psychiatry 1998;65:119–121.
- Adamson DJA, Laing RBS, Nathwani D: Alcoholism, hyponatremia and central neurological damage: More than pontine myelinolysis? Scot Med J 1992;37:83–84.
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