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Case Report

Alcoholic Case of Central Pontine Myelinolysis with Mainly Cerebellar Signs

Ozgur-Ilhan I.a · Demirbas H.a · Yalcın G.A.a · Yucesan C.b · Dogan Y.B.a

Author affiliations

Departments of aPsychiatry and bNeurology, Ankara University School of Medicine, Ankara, Turkey

Related Articles for ""

Eur Addict Res 2005;11:155–156

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Article / Publication Details

First-Page Preview
Abstract of Case Report

Published online: July 09, 2008
Issue release date: June 2005

Number of Print Pages: 2
Number of Figures: 1
Number of Tables: 0

ISSN: 1022-6877 (Print)
eISSN: 1421-9891 (Online)

For additional information: https://www.karger.com/EAR

Abstract

The etiology of central pontine myelinolysis (CPM) is usually related to rapid correction of hyponatremia and alcoholism. Here a case with CPM predominated by cerebellar signs is described, and the neuropsychological assessment of the case is presented as well. Blood biochemistry revealed a normal sodium level and neuropsychological examination revealed impairment in attention and concentration, reduced immediate memory span, and impaired delayed recall. Further studies are needed to discover whether these neuropsychological signs are specific for CPM or due to alcoholism in general.

© 2005 S. Karger AG, Basel


References

  1. Skullerud K, Andersen N, Lundevall J: Cerebral lesions and causes of death in male alcoholics. Int J Legal Med 1991;104:209–213.
  2. Pirzada NA, Ali II: Central pontine myelinolysis. Mayo Clin Proc 2001;76:559–562.
  3. Vermetten E, Rutten SJE, Boon PJ, Hofman PAM, Leentjens AFG: Neuropsychiatric and neuropsychological manifestations of central pontine myelinolysis. Gen Hosp Psychiatry 1999;21:296–302.
  4. Kom-Lubetzki I, Virozub Y, Orbach H: Central pontine myelinolysis after alcohol withdrawal. Isr Med Assoc J 2002;4:656.
    External Resources
  5. Garzon T, Mellibovsky L, Roquer J, Perich X, Diez-Perez A: Ataxic form of central pontine myelinolysis. Lancet Neurol 2002;1:517–518.
  6. Seiser A, Schwarz S, Aichinger-Steiner MM, Funk G, Schnider P, Brainin M: Parkinsonism and dystonia and central pontine and extrapontine myelinolysis. J Neurol Neurosurg Psychiatry 1998;65:119–121.
  7. Adamson DJA, Laing RBS, Nathwani D: Alcoholism, hyponatremia and central neurological damage: More than pontine myelinolysis? Scot Med J 1992;37:83–84.

Article / Publication Details

First-Page Preview
Abstract of Case Report

Published online: July 09, 2008
Issue release date: June 2005

Number of Print Pages: 2
Number of Figures: 1
Number of Tables: 0

ISSN: 1022-6877 (Print)
eISSN: 1421-9891 (Online)

For additional information: https://www.karger.com/EAR


Copyright / Drug Dosage / Disclaimer

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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