European Surgical Research

Original Paper

Serum β-Endorphin Levels in Morbidly Obese Patients: The Effect of Vertical Banded Gastroplasty

Karayiannakis A.J.a · Zbar A.b · Makri G.G.a · Syrigos K.c · Athanasiadis L.d · Alexiou D.a · Bastounis E.A.a

Author affiliations

a First Department of Surgery, University of Athens, Laikon Hospital, Athens, Greece; b Department of Surgery, Royal Postgraduate Medical School, London, UK; c Endocrinology Unit, First Department of Internal Medicine, University of Athens, Laikon Hospital, Athens, Greece; d Department of Psychiatry, St George’s Hospital, Medical School, London, UK

Keywords: β-EndorphinMorbid obesitySurgeryVertical banded gastroplastyWeight loss

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Eur Surg Res 1998;30:409–413
https://doi.org/10.1159/000008606

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: December 09, 1998
Issue release date: November – December

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 2

ISSN: 0014-312X (Print)
eISSN: 1421-9921 (Online)

For additional information: https://www.karger.com/ESR

Abstract

The associations between serum β-endorphin levels and clinical and metabolic variables as well as β-endorphin changes after surgically induced weight loss were investigated in 43 morbidly obese patients. A significant positive correlation between β-endorphin and body weight, degree of body weight increase and ACTH was found preoperatively. Only body weight was independently associated with β-endorphin levels. Twelve months following vertical banded gastroplasty, there was an extensive weight loss in all patients and improvement in their metabolic profile. A significant reduction in β-endorphin levels which was proportional to the extent of weight loss was also observed.



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References

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: December 09, 1998
Issue release date: November – December

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 2

ISSN: 0014-312X (Print)
eISSN: 1421-9921 (Online)

For additional information: https://www.karger.com/ESR

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1998, Vol.30, No. 6

November – December

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