Digestive Diseases
Original Paper
Gastroesophageal Reflux in Healthy Subjects Induced by Two Different Species of Chilli (Capsicum annum)Milke P.a · Diaz A.a · Valdovinos M.A.a · Moran S.baDepartment of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, and bResearch Laboratory of Gastroenterology, Hospital de Pediatría, Centro Médico Nacional, Siglo XXI, IMSS, México, D.F., Mexico
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Article / Publication Details
Published online: May 12, 2006
Issue release date: May 2006
Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 2
ISSN: 0257-2753 (Print)
eISSN: 1421-9875 (Online)
For additional information: https://www.karger.com/DDI
Abstract
Background: Although the ingestion of chilli has been associated with gastroesophageal reflux (GER) symptoms, there are no studies that have explored the effect of a chronic ingestion of different kinds of chilli with a variable content of capsaicin as a cause of GER. Methods: The effect of chilli on esophageal 24-hour pH monitoring was studied in 12 healthy subjects without GER symptoms before and after of ingestion one of two kinds of chilli. Patients were randomized to ingest 3 g daily of cascabel chilli (Capsicum annum coraciforme containing 880 ppmof capsaicin) or ancho chilli (Capsicum annum grossum containing 488 ppm of capsaicin). Results: After chilli ingestion, the Johnson De Meester Index (JDI) increased significantly [basal: 7 (1–14), after chilli: 13 (2–69), p = 0.0047]. When considering both kinds of chilli separately, the JDI varied, although nonsignificantly, with the ancho chilli [basal: 3 (1–8), after chilli: 10 (2–69), p = 0.11], and significantly with the cascabel chilli [basal: 10 (5–14), after chilli: 18 (2–44), p = 0.028]. Conclusion: Our results suggest that the chronic ingestion of chilli induces GER, and that the magnitude of the induced reflux seems to be related to the kind of chilli.
© 2006 S. Karger AG, Basel
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Article / Publication Details
Published online: May 12, 2006
Issue release date: May 2006
Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 2
ISSN: 0257-2753 (Print)
eISSN: 1421-9875 (Online)
For additional information: https://www.karger.com/DDI
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