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Polypill Strategy vs. Prevention Clinics for Stroke Prevention

Amarenco P.

Author affiliations

Department of Neurology and Stroke Center, Bichat Hospital, Denis Diderot University and Medical School, Paris, France

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Cerebrovasc Dis 2006;21:35–40

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Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: February 17, 2006
Issue release date: February 2006

Number of Print Pages: 6
Number of Figures: 2
Number of Tables: 1

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: https://www.karger.com/CED

Abstract

Thirty years of clinical trials have demonstrated that stroke can be prevented by reducing blood pressure to less than 140/90 mm Hg or by a further decrease of 10/5 mm Hg when blood pressure is controlled, by reducing LDL cholesterol by at least 1 mmol/l (39 mg/dl), and by inhibiting platelet aggregation. The (too simplistic) concept of the polypill strategy combining pharmacologic agents to achieve these goals is supposed to reduce the risk by 80% overall. However, reducing general salt and sugar intake, giving up smoking, developing prevention clinics with prevention nurses to improve adherence to preventive treatments, as well as decreasing poverty and malnutrition, increasing the level of hygiene, fighting against infectious diseases and financially helping developing countries are all combined necessary approaches to decrease the worldwide burden of stroke and other vascular diseases.

© 2006 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: February 17, 2006
Issue release date: February 2006

Number of Print Pages: 6
Number of Figures: 2
Number of Tables: 1

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: https://www.karger.com/CED


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