Dialysis, Ultrafiltration, and Blood PressureBergström J. · Asaba H. · Fürst P. · Oulès R.
St Erik’s Hospital, Stockholm, Sweden
Hiroyuki Asaba, MD, PhD
Asaba Medical Research Foundation
4584, 2-Chome, Tai, Tamano City 706-0001 (Japan)
Tel. +81 863 32 11 22, Fax +81 863 32 16 13, E-Mail Konan@tamano.or.jp
Do you have an account?
The effect of ultrafiltration on blood pressure was compared in six patients with problems of overhydration during single-pass dialysis, ultrafiltration only (the fluid bypassing the dialyser) and recirculation dialysis (using the RP 6 dialyser and the 75 l Rodial system). Adequate ultrafiltration during single-pass dialysis was hampered by symptomatic hypotension. However, during recirculation dialysis as well as during ultrafiltration without dialysis much more rapid ultrafiltration was tolerated without a fall in blood pressure. A considerable fall in plasma osmolality occurred with single-pass dialysis, whereas only a small decrease occurred with recirculation dialysis and no change with ultrafiltration only. We conclude that a rapid fall in plasma osmolality interferes with blood pressure regulation and that ultrafiltration is far better tolerated provided that osmotic shifts are avoided or minimised.
© 2006 S. Karger AG, Basel
Alwall, N (1947) Acta Medica Scandinavica, 128:317.
Cambi V, Savazzi G, Arisi L, Bignardi L, Bruschi G, Rossi E, Migone L (1974) Proceedings of the European Dialysis and Transplant Association, 11. Pitman Medical, Tunbridge Wells, p 112.
Chaney AL, Marbach EP (1962) Clinical Chemistry, 8:130.
Emerson TE Jr, Scott JB, Haddy FJ (1970) American Journal of Physiology, 218:234.
Haddy FJ, Overbeck HS (1962) Journal of the Arkansas Medical Society, 58:477.
Haddy FJ, Scott JB, Emerson TE Jr, Overbeck HW, Daugherty RM Jr (1969) CirculationResearch, 24–25:1–59.
Hoppe WJ, Emerson TE (1974) American Heart Journal, 88:198.
Man NK, Granger A, Rondon-Nucete M, Zingraff J, Jungers P, Sausse A, Funck-Brentano JL (1973) Proceedings of the European Dialysis and Transplant Association, 10. Pitman Medical, London, p 236.
Stewart WK, Fleming LW, Manuel MA (1972) Proceedings of the European Dialysis and Transplant Association, 9. Pitman Medical, London, p 111.
Article / Publication Details
Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.