Original Research Article
Investigating the Enhancing Effect of Music on Autobiographical Memory in Mild Alzheimer’s DiseaseIrish M.a, b · Cunningham C.J.a · Walsh J.B.a · Coakley D.a · Lawlor B.A.a · Robertson I.H.b · Coen R.F.a
aMercer’s Institute for Research on Ageing, St. James’s Hospital, Dublin, and bTrinity College Institute for Neuroscience and Department of Psychology, Trinity College, Dublin, Ireland
Do you have an account?
- Rent for 48h to view
- Buy Cloud Access for unlimited viewing via different devices
- Synchronizing in the ReadCube Cloud
- Printing and saving restrictions apply
Rental: USD 8.50
Cloud: USD 20.00
The enhancing effect of music on autobiographical memory recall in mild Alzheimer’s disease individuals (n = 10; Mini-Mental State Examination score >17/30) and healthy elderly matched individuals (n = 10; Mini-Mental State Examination score 25–30) was investigated. Using a repeated-measures design, each participant was seen on two occasions: once in music condition (Vivaldi’s ‘Spring’ movement from ‘The Four Seasons’) and once in silence condition, with order counterbalanced. Considerable improvement was found for Alzheimer individuals’ recall on the Autobiographical Memory Interview in the music condition, with an interaction for condition by group (p < 0.005). There were no differences in terms of overall arousal using galvanic skin response recordings or attentional errors during the Sustained Attention to Response Task. A significant reduction in state anxiety was found on the State Trait Anxiety Inventory in the music condition (p < 0.001), suggesting anxiety reduction as a potential mechanism underlying the enhancing effect of music on autobiographical memory recall.
© 2006 S. Karger AG, Basel
Heindel WC, Salmon DP, Butters N: Cognitive approaches to the memory disorders of demented patients; in Sutker PB, Adams HE (eds): Comprehensive Handbook of Psychopathology, ed 2. New York, Plenum Press, 1993, pp 735–761.
Baddeley AD: Working Memory. Oxford, Oxford University Press, 1986.
Conway MA: Autobiographical Memory: An Introduction. Buckingham, Open University Press, 1990.
- Addis DR, Tippett LJ: Memory of myself: autobiographical memory and identity in Alzheimer’s disease. Memory 2004;12:56–74.
- Small GW: Treatment of Alzheimer’s disease: current approaches and promising developments. Am J Med 1998;104:32–38.
- Rauscher FH, Shaw GL, Ky CN: Music and spatial task performance. Nature 1993;365:611.
Leng X, Shaw GL: Toward a neural theory of higher brain function using music as a window. Concepts Neurosci 1991;2:229–258.
- Thompson WF, Schellenberg EG, Husain G: Arousal, mood, and the Mozart effect. Psychol Sci 2001;12:248–251.
- Steele KM, Bass KE, Crook MD: The mystery of the Mozart effect: failure to replicate. Psychol Sci 1999;10:366–369.
Chabris CF: Prelude or requiem for the ‘Mozart effect?’ Nature 1999;400:826–827.
- Dittuno PL, Mann VA: Right hemisphere specialisation for mental rotation in normals and brain damaged subjects. Cortex 1990;26:177–188.
Koger SM, Brotons M: Music therapy for dementia symptoms. Cochrane Database Syst Rev 2000:CD001121.
Stefano GB, Zhu W, Cadet P, Salamon E: Music alters constitutively expressed opiate and cytokine processes in listeners. Med Sci Monit 2004;10:MS18–27.
Vink AC: The problem of agitation in elderly people and the potential benefit of music therapy; in Aldridge D (ed): Music Therapy in Dementia Care. London, Jessica Kingsley Publishers, 2000, pp 102–119.
- Ragneskog H, Kihlgren M, Karlsson I, Norberg A: Dinner music for demented patients: analysis of video-recorded observations. Clin Nurs Res 1996;5:262–282.
- Clark ME, Lipe AW, Bilbrey M: Use of music to decrease aggressive behaviours in people with dementia. J Gerontol Nurs 1998;24:10–17.
- Lucero M, Hutchinson S, Leger-Krall S, Wilson H: Wandering in Alzheimer’s dementia patients. Clin Nurs Res 1993;2:160–175.
- Sung HC, Chang AM: Use of preferred music to decrease agitated behaviours in older people with dementia: a review of the literature. J Clin Nurs 2005;14:1133–1140.
Vink AC, Birks JS, Bruinsma MS, Scholten RJ: Music therapy for people with dementia. Cochrane Database Syst Rev 2004:CD003477.
- Grasel E, Wiltfang J, Kornhuber J: Non-drug therapies for dementia: an overview of the current situation with regard to proof of effectiveness. Dement Geriatr Cogn Disord 2003;15:115–125.
- Suzuki M, Kanamori M, Watanabe M, Nagasawa S, Kojima E, Ooshiro H, Nakahara D: Behavioural and endocrinological evaluation of music therapy for elderly patients with dementia. Nurs Health Sci 2004;6:11–18.
- Parker GJ, Luzzi S, Alexander DC, Wheeler-Kingshott CA, Ciccarelli O, Lambon Ralph MA: Lateralisation of ventral and dorsal auditory language pathways in the human brain. Neuroimage 2005;24:656–666.
Foster NA, Valentine ER: The effect of concurrent music on autobiographical recall in dementia clients. Musicae Sci 1998;2:143–155.
- Foster NA, Valentine ER: The effect of auditory stimulation on autobiographical recall in dementia. Exp Aging Res 2001;27:215–228.
- Greene JD, Hodges JR, Baddeley A: Autobiographical memory and executive function in early dementia of the Alzheimer type. Neuropsychologia 1995;33:1647–1670.
Kopelman MD, Wilson BA, Baddeley AD: The Autobiographical Memory Interview (Manual). Bury St. Edmunds, Thames Valley Test Company, 1991.
Spielberger CD, Gorsuch RL, Lushene RE: The State Trait Anxiety Inventory. Mountain View, Consulting Psychologists Press, 1970.
BIOPAC Systems, Goleta.
- Critchley HD, Melmed RN, Featherstone E, Mathias CJ, Dolan RJ: Brain activity during biofeedback relaxation: a functional neuroimaging investigation. Brain 2001;124:1003–1012.
Dawson ME, Schell AM, Filion DL: The electrodermal system; in Cacioppo JT, Tassinary LG, Berntson GG (eds): Handbook of Psychophysiology, ed 2. Cambridge, Cambridge University Press, 1993, pp 200–223.
- O’Connell RG, Bellgrove MA, Dockree PM, Robertson IH: Reduced electrodermal responses to errors predicts poor sustained attention performance in attention deficit/hyperactivity disorder. Neuroreport 2004;15:1–5.
- Sturm W, Willmes K: On the functional neuroanatomy of intrinsic and phasic alertness. Neuroimage 2001;14:S76–S84.
- Robertson IH, Manly T, Andrade J, Baddeley BT, Yiend J: ‘Oops!’: performance correlates of everyday attentional failures in traumatic brain injured and normal subjects. Neuropsychologia 1997;35:747–758.
- Manly T, Owen AM, McAvenue L, Datta A, Lewis GH, Scott SK, Rorden C, Pickard J, Robertson IH: Enhancing the sensitivity of a sustained attention task to frontal damage: convergent clinical and functional imaging evidence. Neurocase 2003;9:340–349.
- Sarter M, Givens B, Bruno JP: The cognitive neuroscience of sustained attention: where top-down meets bottom-up. Brain Res Brain Res Rev 2001;35:146–160.
- McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM: Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease. Neurology 1984;34:939–944.
- Yesavage JA, Brink TL, Rose TL, Lum O: Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 1983;17:37–49.
- Folstein MF, Folstein SE, McHugh PR: Mini-Mental State: a practical method for grading the cognitive state of the patient for the clinician. J Psychiatr Res 1975;12:189–198.
- Manos PJ: Ten-point clock test sensitivity for Alzheimer’s disease in patients with MMSE scores greater than 23. Int J Geriatr Psychiatry 1999;14:454–458.
Vivaldi A: The Four Seasons: La Primavera (Spring). Concerto in E Major (RV269). Lucerne Festival Strings. Director: Rudolf Baumgartner, 1966. Hamburg, Polydor International.
Chasin M: Decibel (Loudness) Comparison Chart. Centre for Human Performance and Health, 1997. Copyright by Galen Carol Audio, San Antonio, 1997–2003.
- O’Keefe FM, Dockree PM, Robertson IH: Poor insight in traumatic brain injury mediated by impaired error processing? Evidence from electrodermal Activity. Brain Res Cogn Brain Res 2004;22:101–112.
Stern R, Ray WJ, Quigley KS: Psychophysiological Recordings. New York, Oxford University Press, 2001, pp 206–220.
- Conway MA, Haque S: Overshadowing the reminiscence bump: memories of a struggle for independence. J Adolesc Dev 1993;6:35–44.
- Kazui H, Hashimoto M, Hirono N, Imamura T, Tanimukai S, Hanihara T, Ikeda M, Komori K, Ikejiri Y, Mori E: A study of remote memory impairment in Alzheimer’s disease by using The Family Line Test. Dement Geriatr Cogn Disord 2000;11:53–58.
- Khalfa S, Peretz I, Blondin JP, Manon R: Event-related skin conductance responses to musical emotions in humans. Neurosci Lett 2002;328:145–149.
Yerkes RM, Dodson JD: The relation of strength of stimulus to rapidity of habit formation. J Comp Physiol Psychol 1908;18:459–482.
- Peretz I: Processing of local and global musical Information by unilateral brain-damaged patients. Brain 1990;113:1185–1205.
- Lechevalier B, Platel H, Eustache F: Neuropsychology of musical identification. Rev Neurol (Paris) 1995;151:505–510.
- Platel H, Price C, Baron JC, Wise R, Lambert J, Frackowiak RS, Lechevalier B, Eustache F: The structural components of music perception: a functional anatomical study. Brain 1997;120:229–243.
- Dritschel BH, Williams JM, Baddeley AD, Nimmo-Smith I: Autobiographical fluency: a method for the study of personal memory. Mem Cognit 1992;20:133–140.
- Balota DA, Cortese MJ, Duchek JM, Adams D, Roediger HL, McDermott KB, Yerys BE: Veridical and false memories in healthy older adults and in dementia of the Alzheimer’s type. Cognit Neuropsychol 1999;16:361–384.
- Bower GH: Mood and memory. Am Psychol 1981;36:129–148.
McNair DM, Lorr M, Droppleman LF: Profile of Mood States. San Diego, Educational and Industrial Testing Service, 1992.
- Walter H, Kiefer M, Erk S: Content, context and cognitive style in mood-memory interactions. Trends Cognit Sci 2003;7:433–434.
- Schmidt LA, Trainor LJ: Frontal brain electrical activity (EEG) distinguishes valence and intensity of musical emotions. Cognit Emot 2001;15:487–500.
- Nantais KM, Schellenberg EG: The Mozart effect: an artifact of Preference. Psychol Sci 1999;10:370–373.
- Wheeler MA, Stuss DT, Tulving E: Toward a theory of episodic memory: the frontal lobes and autonoetic consciousness. Psychol Bull 1997;121:331–354.
Article / Publication Details
Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.