Ophthalmologica

Original Paper

Corneal Curvature after Penetrating Keratoplasty before and after Suture Removal: A Comparison between Keratoconus and Fuchs’ Dystrophy

Seitz B.a · Langenbucher A.a · Szentmary N.b · Naumann G.O.H.a

Author affiliations

aDepartment of Ophthalmology, University of Erlangen-Nürnberg, Erlangen, Germany; bDepartment of Ophthalmology, Semmelweis University, Budapest, Hungary

Keywords: Fuchs’ dystrophyKeratoconusPostkeratoplasty outcomeVisual acuityAstigmatismCentral corneal powerTopographic regularityCorneal curvature

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Ophthalmologica 2006;220:302–306
https://doi.org/10.1159/000094619

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: October 06, 2005
Accepted: January 13, 2006
Published online: September 07, 2006
Issue release date: September 2006

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 2

ISSN: 0030-3755 (Print)
eISSN: 1423-0267 (Online)

For additional information: https://www.karger.com/OPH

Abstract

Purpose: To assess the differences concerning corneal curvature and visual acuity after penetrating keratoplasty (PKP) comparing keratoconus (KC) and Fuchs’ dystrophy (FUCHS). Methods: Inclusion criteria for this prospective, comparative, interventional study were: (1) one surgeon, (2) central round nonmechanical excimer laser PKP without previous surgery, (3) FUCHS (n = 35) or KC (n = 52), (4) standardized graft size (7.5–8.0 mm) and technique, 16-bite double running cross-stitch suture. In 69% of FUCHS, a triple procedure was performed. The main outcome measures were: keratometric astigmatism, surface regularity index, surface asymmetry index, keratometric central corneal power and best-corrected visual acuity before (1.2 ± 0.4 years) and after suture removal (1.8 ± 0.6 years). Results: Astigmatism did not differ significantly between KC and FUCHS (p > 0.1) before (3.3 dpt vs. 3.5 dpt median) and after suture removal (2.5 dpt vs. 3.0 dpt). Surface regularity index and surface asymmetry index were significantly higher in FUCHS than in KC (p < 0.001) at both time stages. Central power was significantly greater in KC than in FUCHS (p < 0.001) with sutures in place. Due to a significant steepening in FUCHS and flattening in KC, this difference was no longer present after suture removal. Visual acuity in KC exceeded that in FUCHS before (0.68 vs. 0.60) and even more after suture removal (0.86 vs. 0.60; p < 0.001). Conclusions: In KC, keratometric astigmatism is not higher than in FUCHS after PKP. After suture removal, graft topography in KC and FUCHS may be expected to regularize and the excessive corneal flattening in FUCHS to normalize in the mid-term.

© 2006 S. Karger AG, Basel



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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: October 06, 2005
Accepted: January 13, 2006
Published online: September 07, 2006
Issue release date: September 2006

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 2

ISSN: 0030-3755 (Print)
eISSN: 1423-0267 (Online)

For additional information: https://www.karger.com/OPH

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2006, Vol.220, No. 5

September 2006

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