Extracellular Accumulations in the Avian Pituitary Gland: Histochemical Analysis in Two Species of Indian Wild BirdsMohanty B.
Department of Zoology, University of Allahabad, Allahabad, India
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Extracellular accumulations of two distinct types, colloid-filled follicles and fibrous-material-containing cysts, were observed in the pituitary gland of two species of Indian wild birds, Halcyon smyrnensis perpulchra and Lonchura striata striata. Colloid follicles were regular structures and distributed throughout the pars distalis (PD). The fibrous cysts were irregular structures, bigger than the colloid follicles and mostly observed towards the ventral margin of the PD. Sometimes disruption of the outer margin with depletion of fibrous material from the cavity was observed. Hormone-secreting cells of various types, anti-adrenocorticotropic-hormone-, anti-prolactin-, anti-growth-hormone- and anti-luteinizing-hormone-immunoreactive cells were encountered bordering both the colloid follicles and fibrous cysts. Neither the colloid nor the fibrous material showed any immunoreaction to any of the pituitary hormone antisera. On histochemical staining colloid was positive to periodic acid-Schiff (PAS) and fibrous materials stained with Alcian blue-PAS-orange G staining. Colloid depositions in the pituitary gland of these two wild birds were correlated to age, more in numbers in the adult birds than in the young ones. Fibrous-material-containing cysts were elucidated in the pituitary gland of adult birds only. These were more prevalent in the pituitary of reproductively active birds. Regular morphology of the colloid follicles, overall distribution in the adenohypophysis and dense nature of deposition of the colloid suggest the accumulation of this type may be the secretory products of both granulated and agranulated pituitary cell types. Absence of immunoreactivity of the colloid against pituitary hormone antisera points out that the storage form may differ chemically from the bioactive hormones. The spatial distribution of fibrous-material-containing cysts mostly towards the ventral PD, observations of immunoreactive cell fragmentations inside the cysts, and their disrupted margins suggest these structures may have some role in discharging the intraglandular degradation products.
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- Anthony, E.L.P, A.W. Gustafson (1984) A quantitative study of pituitary colloid in the bat Myotislucifuguslucifugus in relation to age, sex, and season. Am J Anat 169: 89–100.
- Azzali, G., M.L. Arcari, B. Spaggiari, G. Romita (2003) Ultrastructural aspects of the follicular cells of the pars tuberalis in bats related to the seasonal cycle. Anat Rec 273A: 763–771.
- Benjamin, M. (1981) Cysts (large follicles) and colloid in pituitary glands. Gen Comp Endocrinol 45: 425–445.
- Boyd, W.H., A. Peters (1983) Bovine pituitary intraglandular colloid: a transport medium. Acta Biol Hung 34: 357–362.
- Boyd, W.H., R. Krogsrud (1986) ACTH in bovine pituitary intraglandular colloid, the holocrine secretion of intermediate lobe cells. Acta Biol Hung 37: 225–233.
- sBoyd, W.H., R. Krogsrud, D. Jichici (1986) Presence of met-enkephalin in bovine pituitary intraglandular colloid of intermediate lobe origin. Biochem Biophys Res Commun 139: 480–486.
- Ciocca, D.R., L.A. Puy, A.O. Stati (1984) Constitution and behaviour of follicular structures in the human pituitary gland. Am J Pathol 115: 165–174.
Dar, A.P., A.G. Sathyanesan (1985) Micromorphology of the cysts in the proximal pars distalis of the pituitary of the Chana punctatus (Pisces). Microscopie 42: 45–51.
- Fleming, J.S, N.M Hope, C.J Bolter (1999) Clusterin is expressed in the anterior and intermediate lobes, but not in the posterior pituitary of sheep. J Mol Endocrinol 23: 199–208.
- Fukuda, T. (1973) Agranular stellate cells (so-called follicular cells) in human fetal and adult adenohypophysis and in pituitary adenoma. Virchows Arch A Pathol Pathol Anat 359: 19–30.
- Harrisson, F., J. Van Hoof, L. Vakaet (1982) The relationship between the folliculo-stellate network and the thyrotropic cells of the avian adenohypophysis. Cell Tissue Res 226: 97–111.
Holmes, R.L., J.N. Ball (1974) The Pituitary Gland: A Comparative Account. London, Cambridge University Press.
- Inoue, K., C. Mogi, S. Ogawa, M. Tomida, S. Miyai (2002) Are folliculo-stellate cells in the anterior pituitary gland supportive cells or organ-specific stem cells? Arch Physiol Biochem 110: 50–53.
- Kameda, Y. (1991) Occurrence of colloid-containing follicles in the pars distalis of pituitary glands from aging guinea pigs. Cell Tissue Res 263: 115–124.
- Matsuo, S., A. Vitmus, J.R. King, D.S. Farner (1969) Light-microscope studies of the cytology of the adenohypophysis of the white-crowned sparrow, Zonotrichia leucophrys gambelli. Z Zellforsch Mikrosk Anat 95: 143–176.
- Mohamed, F., T. Fogal, S. Dominguez, L. Scardapane, J. Guzman, R.S. Piezzi (2000) Colloid in the pituitary pars distalis of viscacha (Lagostomus maximus maximus): ultrastructure and occurrence in relation to season, sex, and growth. Anat Rec 258: 252– 261.
- Mohanty, B., S. Das, D.R Naik (1996) Immunoelectron microscopy of corticotropes and melanotropes in the pituitary gland of European ferret, Mustela putorius furo. Acta Anat 157: 126–134.
- Ogawa, S., E.F Couch, M. Kubo, T. Sakai, K. Inoue (1996) Histochemical study of follicles in the senescent porcine pituitary gland. Arch Histol Cytol 59: 467–478
- Ogawa, S., Y. Ishibashi, Y. Sakamoto, K. Kitamura, M. Kubo, T. Sakai, K. Inoue (1997) The glycoproteins that occur in the colloids of senescent porcine pituitary glands are clusterin and glycosylated albumin fragments. Biochem Biophys Res Commun 234: 712–718.
- Osamura, R.Y, K. Watanabe (1978) An immunohistochemical study of epithelial cells in the posterior lobe and pars tuberalis of the human adult pituitary gland. Cell Tissue Res 194: 513–524.
- Sternberger, L.A, P.H. Hardy Jr., J.J. Cuculis, H.G. Meyer (1970) The unlabelled antibody enzyme method of immunochemistry. Preparation and properties of soluble antigen antibody complex (horseradish peroxidase antiperoxidase) and its use in identification of spirochetes. J Histochem Cytochem 18: 315–333.
Tixier-Vidal, A., B.K. Follet (1973) The adenohypophysis; in Farner, D.S, J.R. King (ed.): Avian Biology. New York, Academic Press, vol 3, pp 110–182.
- Watanabe, Y.G. (1991) The occurrence and developmental origin of epithelial cysts in the rat and mouse adenohypophysis. Arch Histol Cytol 54: 511–518.
Wingstrand, K.G. (1966) Comparative anatomy and evolution of the hypophysis; in Harris, G.W., B.T. Donovan (ed.): The Pituitary Gland. London, Butterworths, pp 58–126.
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