Audiology and Neurotology
Original Paper
Mechanism and Rate of Middle Ear Fluid AbsorptionPetrova P.a · Freeman S.b · Sohmer H.baDepartment of Otolaryngology, Head and Neck Surgery, Hadassah University Hospital, and bDepartment of Physiology, Hebrew University, Hadassah Medical School, Jerusalem, Israel
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Article / Publication Details
Received: December 23, 2005
Accepted: September 27, 2006
Published online: January 25, 2007
Issue release date: April 2007
Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 0
ISSN: 1420-3030 (Print)
eISSN: 1421-9700 (Online)
For additional information: https://www.karger.com/AUD
Abstract
Several mechanisms have been suggested to explain the clearance of fluids from the middle ear. These include a pumping action through the eustachian tube, mucociliary beating through the tube, outflow of water to the blood due to osmotic gradients and an active Na+ transport driving water absorption. In order to assess these mechanisms, the middle ear cavity of paralyzed, ventilated (eustachian tube occluded) guinea pigs was filled with fluids varying in osmotic pressure (hypotonic, isotonic, hypertonic) to which a vertical tube was attached. The change in height of fluid in the tube was taken as a measure of changes in middle ear fluid volume. A greater fluid volume reduction was seen with the hypotonic (1/5 saline) solution. A small volume increase was observed with the hypertonic solution. These results provide evidence that in these experimental conditions, water absorption due to osmotic gradients can contribute to middle ear fluid clearance.
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Article / Publication Details
Received: December 23, 2005
Accepted: September 27, 2006
Published online: January 25, 2007
Issue release date: April 2007
Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 0
ISSN: 1420-3030 (Print)
eISSN: 1421-9700 (Online)
For additional information: https://www.karger.com/AUD
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