Effect of Frequent Rinses with Isomaltulose (Palatinose®) Solution on Acid Production in Human Dental PlaqueTopitsoglou V. · Sasaki N. · Takazoe I. · Frostell G.
Department of Cariology, Odontological Clinics, Karolinska Institute, Huddinge, Sweden
Vassiliki Topitsoglou, Department of Preventive Dentistry and Periodontics, Dental School, University of Thessaloniki, Thessaloniki (Greece)
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Acid production from glucose and isomaltulose (Palatinose®) in dental plaque suspensions was studied before and after subjects rinsed their mouths 6 times daily for 6 weeks with a 15% w/v isomaltulose solution. The mean acid production from isomaltulose, expressed in percent of that from glucose, increased significantly (p < 0.01) after the rinsing period. In vivo plaque pH changes caused by a mouth rinse with 10 ml of a 15% w/v glucose or isomaltulose solution were determined also, before and after the rinsing period. The pH decreases from isomaltulose were significantly more pronounced after the rinsing period (p < 0.01) and the raw pH values were about 0.57 units lower than before (p < 0.001), but never below pH 6.2. Isomaltulose was considerably less acidogenic than glucose before as well as after the isomaltulose rinsing period (p < 0.001).
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