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Neuropsychobiology 2011;63:43–51

Is Alpha Wave Neurofeedback Effective with Randomized Clinical Trials in Depression? A Pilot Study

Choi S.W.a · Chi S.E.b · Chung S.Y.c · Kim J.W.c · Ahn C.Y.b · Kim H.T.b

Author affiliations

aDepartment of Industrial and Advertising Psychology, Daejeon University, Daejeon, bDepartment of Psychology, Korea University, and cHwabyung/Stress Clinic, Kyunghee University East-West Neo Medical Center, Seoul, Korea

Corresponding Author

Hyun Taek Kim, PhD

Department of Psychology and Laboratory of Behavioral Neuroscience

Korea University, No. 414, Law Bldg.(old).1,5-Ga

Anam-dong Sungbuk-ku, Seoul 136-701 (Korea)

Tel. +82 2 3290 2530, Fax +82 2 3290 2662, E-Mail neurolab@korea.ac.kr

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Frontal asymmetric activation has been proposed to be the underlying mechanism for depression. Some case studies have reported that the enhancement of a relative right frontal alpha activity by an asymmetry neurofeedback training leads to improvement in depressive symptoms. In the present study, we examined whether a neurofeedback training designed to increase the relative activity of the right frontal alpha band would have an impact on symptoms of depressive subjects suffering from emotional, behavioral, and cognitive problems. Our results indicated that the asymmetry neurofeedback training increased the relative right frontal alpha power, and it remained effective even after the end of the total training sessions. In contrast to the training group, the placebo control group did not show a difference. The neurofeedback training had profound effects on emotion and cognition. First, we replicated earlier findings that enhancing the left frontal activity led to alleviation of depressive symptoms. Moreover, cognitive tests revealed that the asymmetry training improved performance of executive function tests, whereas the placebo treatment did not show improvement. We preliminarily concluded that the asymmetry training is important for controlling and regulating emotion, and it may facilitate the left frontal lobe function.

© 2010 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: September 21, 2009
Accepted: March 16, 2010
Published online: November 09, 2010

Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 0

ISSN: 0302-282X (Print)
eISSN: 1423-0224 (Online)

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