Acute Ischemic Stroke Therapy
A Clinical OverviewZülküf Önal M.a · Fisher M.b
a Department of Neurology, Akdeniz Üniversitesi Araştirma Hastahanesi, Akdeniz Üniversitesi Tip Fakültesi, Antalya, Turkey; b Department of Neurology and Radiology, University of Massachusetts Medical School, Memorial Health Care, Worcester, Mass., USA
Mehmet Zülküf Önal, MD, Department of Neurology, Akdeniz Üniversitesi Araştirma Hastahanesi, Akdeniz Üniversitesi Tip Fakültesi, TR-07058 Antalya (Turkey), Tel. (242) 2274343, Fax (242) 2274490, E-Mail firstname.lastname@example.org
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Acute ischemic stroke therapy has two basic therapies, dissolving the intravascular occlusion by thrombolytic therapy and protecting the brain from the harmfull cellular, and metabolic consequences of ischemic injury by neuroprotective therapy. It seems most likely that the methods that will be used to treat the acute ischemic stroke patient will be multiple, likely a combination of thrombolytic therapy for early reperfusion and neuroprotective therapy for maintaining vitality. In the last decade, a number of advances in the field of imaging and pharmacology have been made which should provide meaningful improvement for the management of acute ischemic stroke patients in the near future. This update summarizes recent clinical trials and emphasizes the question of risk versus benefit for the acute ischemic stroke therapies being developed.
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