Pathobiology 1997;65:57–60
(DOI:10.1159/000164104)

Detection of RNA Sequences in Cultures of a Stealth Virus Isolated from the Cerebrospinal Fluid of a Health Care Worker with Chronic Fatigue Syndrome

Case Report

Martin W.

Author affiliations

Center for Complex Infectious Diseases, Rosemead, Calif., USA

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Article / Publication Details

First-Page Preview
Abstract of Late Breaking Research

Received: April 10, 1997
Accepted: April 17, 1997
Published online: October 08, 2008

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1015-2008 (Print)
eISSN: 1423-0291 (Online)

For additional information: https://www.karger.com/PAT

Abstract

A cytopathic stealth virus was cultured from the cerebrospinal fluid of a nurse with chronic fatigue syndrome. Reverse transcriptase-polymerase chain reaction (RT-PCR) performed on the patient’s culture yielded positive results with primer sets based on sequences of a previously isolated African green monkey simian-cytomegalovirus-derived stealth virus. The same primer sets did not yield PCR products when tested directly on DNA extracted from the cultures. The findings lend support to the possibility of replicative RNA forms of certain stealth viruses and have important implications concerning the choice of therapy in this type of patient.

© 1997 S. Karger AG, Basel




Article / Publication Details

First-Page Preview
Abstract of Late Breaking Research

Received: April 10, 1997
Accepted: April 17, 1997
Published online: October 08, 2008

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1015-2008 (Print)
eISSN: 1423-0291 (Online)

For additional information: https://www.karger.com/PAT

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