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Skin Pharmacol Physiol 2013;26:101-107

Serum Ferritin and Vitamin D in Female Hair Loss: Do They Play a Role?

Rasheed H.a · Mahgoub D.a · Hegazy R.a · El-Komy M.a · Abdel Hay R.a · Hamid M.A.a · Hamdy E.b

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Departments of aDermatology and bClinical Pathology, Faculty of Medicine, Cairo University, Cairo, Egypt

Corresponding Author

Rania M. Abdel Hay, MD

13th Abrag Othman

Kornish El Maadi

Cairo 11431 (Egypt)

E-Mail omleila2@yahoo.com

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Aim: Evaluation of serum ferritin and vitamin D levels in females with chronic telogen effluvium (TE) or female pattern hair loss (FPHL), in order to validate their role in these common hair loss diseases. Methods: Eighty females (18 to 45 years old) with hair loss, in the form of TE or FPHL, and 40 age-matched females with no hair loss were included in the study. Diagnosis was based upon clinical examination as well as trichogram and dermoscopy. Serum ferritin and vitamin D2 levels were determined for each participant. Results: Serum ferritin levels in the TE (14.7 ± 22.1 μg/l) and FPHL (23.9 ± 38.5 μg/l) candidates were significantly lower than in controls (43.5 ± 20.4 μg/l). Serum vitamin D2 levels in females with TE (28.8 ± 10.5 nmol/l) and FPHL (29.1 ± 8.5 nmol/l) were significantly lower than in controls (118.2 ± 68.1 nmol/l; p < 0.001). These levels decreased with increased disease severity. Serum ferritin cut-off values for TE and FPHL were 27.5 and 29.4 μg/l, respectively, and those for vitamin D were 40.9 and 67.9 nmol/l. Conclusion: Low serum ferritin and vitamin D2 are associated with hair loss in females with TE and FPHL. Screening to establish these levels in cases of hair loss and supplementing with them when they are deficient may be beneficial in the treatment of disease.

© 2013 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: October 29, 2012
Accepted: December 21, 2012
Published online: February 20, 2013

Number of Print Pages: 7
Number of Figures: 1
Number of Tables: 3

ISSN: 1660-5527 (Print)
eISSN: 1660-5535 (Online)

For additional information: https://www.karger.com/SPP