Lichen scrofulosorum is a rare entity of children and young adults. The cutaneous lesions are typically symptomless papular eruptions, associated with a strong Mantoux reaction, tuberculosis of lymph nodes and/or other organs. Eight patients between the ages of 5 and 36 years were included in this series. Lesions were commonly seen on the trunk, though a case of involvement of the palms and soles was also observed. Pulmonary tuberculosis was seen in 5 adults; 1 patient each had pleural effusion, tuberculous adenitis and tuberculoma, respectively. Histopathological examination typically showed epithelioid cell granulomas around hair follicles. The histogenesis is unclear, a type IV hypersensitivity reaction provoked by chronic tubercular infection is probable. The patients responded well to antituberculous therapy.

1.
Tappeiner G, Wolff K: Tuberculosis and other mycobacterial infections; in Friedberg IM, Eisen AZ, Wolff K, Austen F, Goldsmith LA, Katz SI, Fitzpatrick TB (eds): Dermatology in General Medicine, ed 5. New York, McGraw-Hill, 1999, pp 2274–2292.
2.
Hebra F: Lichen scrofulosorum; in Fagge CH, Pye Smith PH (eds): Diseases of the Skin. London, New Sydenham Society, 1868, p 52.
3.
Smith NP, Ryan TJ, Sanderson KV: Lichen scrofulosorum: A report of four cases. Br J Dermatol 1976;94:319–325.
4.
Hudson PM: Tuberculid (lichen scrofulosorum) secondary to osseous tuberculosis. Clin Exp Dermatol 1976;1:391–394.
5.
Johnson WC: Lichen scrofulosorum; in Graham JH, Johnson WC, Helwig EB (eds): Dermal Pathology. Haferstown, Harper & Row, 1972, p 394.
6.
Vanhooteghem O, Doffiny Y: Lichen scrofulosorum type tuberculid of the face. Dermatology 1996;192:393–395.
7.
Robinson G, Ellis IO, Machennan KA: Immunocytochemistry; in Bancroft JD, Stevens A, Turner DR (eds): Theory and Practice of Histological Techniques, ed 3. Edinburgh, Churchill-Livingstone, 1984, pp 413–436.
8.
Rongioletti F, Clavarino M, Gorton C, Rebora A: Papules on the lower limbs of a woman with cervical lymphadenopathy. Arch Dermatol 1988;124:1425–1426.
9.
Victor T, Jordaans HF, Van Niekerk DJ: Papulonecrotic tuberculid: Identification of Mycobacterium tuberculosis DNA by polymerase chain reaction. Am J Dermatopathol 1992;14:491–495.
10.
Thami GP, Kamivar AJ: Lichenoid sarcoidosis resembling lichen scrofulosorum. Indian J Dermatol 1998;43:26–27.
11.
Sehgal VN, Srivastava G, Sharma VK, Bhalla P, Bohar PC: An appraisal of epidemiologic, clinical, bacteriologic, histopathologic and immunologic parameters in cutaneous tuberculosis. Int J Dermatol 1987;26:521–526.
12.
Morrison JGL, Fourie ED: The papulonecrotic tuberculid from Arthus reaction to lupus vulgaris. Br J Dermatol 1974;91:263–270.
13.
Zukervar P, Perrot H: Les tuberculides: mise au point. Ann Dermatol Vénéréol 1991;118:405–409.
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