Mycobacteria and TB

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Editor(s): Kaufmann, S.H.E. (Berlin)
Hahn, H. (Berlin)

Status: available   
Publication year: 2003
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This book belongs to
Issues in Infectious Diseases , Vol. 2
Editor(s): Mahy, B.W.J. (Bury St. Edmunds)
X + 156 p., 16 fig., 1 in color, 11 tab., hard cover, 2003
Status: available   
ISSN: 1660-1890
e-ISSN: 1662-3819


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Reviews

'This slim volume on tuberculosis is admirable in its brevity and in its clarity. The title reflects a focus in many chapters on the bacterium and its role in pathogenesis (rather than, for example, on clinical issues). There are nine chapters written by experts in their fields, covering TB as a global public health problem, molecular epidemiology, the status of BCG, laboratory diagnosis, chemotherapy and drug resistance, molecular biology, immunology and persistence, and the development of new vaccines and drugs. Chapters are extremely clearly written, and many (importantly) contain a historical perspective as well as describing the current state of knowledge. My only criticism would be to ask for more; for example, something on clinical disease would help balance molecular, cellular and epidemiology perspectives. Yet, the conciseness of the book is also a strength. I recommend this unreservedly as a primer on tuberculosis, and will use it myself for reference.'
Neil Stoker, Royal Veterinary College, London
MICROBIOLOGY TODAY, Vol. 30, August 2003

'Together, the chapters effectively summarize current scientific information essential for Mycobacterium tuberculosis prevention, control, and treatment. This text would be an excellent resource for anyone who wants to be brought up to date on basic scientific research involving tuberculosis and its control.'
Toby L. Merlin, MD, Atlanta, Ga.
(CHEST, Vol. 127, No. 2, 2005)
A valuable update for researchers and clinicians
Tuberculosis remains one of the main fatal infections in humans. With annual morbidity and mortality rates worldwide of 8 and 2 million cases respectively, the disease is far from being eradicated. In fact, the dangerous liaison between TB and HIV, and the increasing incidences of multi-drug resistant strains of Mycobacterium tuberculosis are aggravating the problem. The latest epidemiological data indicate that new drugs and a novel vaccine are urgently needed to control TB adequately.
This volume summarizes the state of the art in the prevention, diagnosis and therapy of TB. In addition, the molecular biology of M. tuberculosis and the immunology of the host response are presented. Researchers are beginning to understand how the immune response controls the pathogen quite efficiently, yet fails to eradicate it completely in the 2 billion people worldwide who are infected but do not develop the disease. Finally, recent strategies towards the development of new vaccines are reviewed.
Scientists investigating the epidemiology, immunology and molecular biology of TB or engaged in vaccine and drug development as well as physicians and social workers treating TB patients will benefit from this timely overview.

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Bibliographic Details
Issues in Infectious Diseases, Vol. 2

Editor(s): Kaufmann, S.H.E. (Berlin)
Hahn, H. (Berlin)
Mycobacteria and TB
ISBN: 978-3-8055-7459-4
e-ISBN: 978-3-318-00878-4
DOI: 10.1159/isbn.978-3-318-00878-4

X + 156 p., 16 fig., 1 in color, 11 tab., hard cover, 2003
Status: available   
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