Parasites and Allergy

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Editor(s): Capron, M. (Lille)
Trottein, F. (Lille)

Status: available   
Publication year: 2006
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Print Version : CHF 178.00, EUR 166.00, USD 209.00
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This book belongs to
Chemical Immunology and Allergy , Vol. 90
Editor(s): Platts-Mills, T.A.E. (Charlottesville, VA)
XII + 202 p., 27 fig., 1 in color, 2 tab., hard cover, 2006
Status: available   
ISSN: 1660-2242
e-ISSN: 1662-2898


Read the reviews

Reviews

'The volume consists of twelve detailed, beautifully written, well illustrated research and review papers by a group of authors (including three Australians) who are internationally-recognised experts in parasite and/or allergic immunology. The subject matter is wide-ranging and includes article on helminth-induced immuno-regulation to food, nematode infection and allergy, schistosomiasis and allergy, the roles of glycans and proteases, helminths and asthma, and the role of mast cells and basophils. Each paper is accompanied by its own reference list that provides a treasure trove of further reading and these alone would make the book worth buying. The subject index is comprehensive and easy to use. A minor criticism is that some of the detailed illustrations are quite small and use a fine font that makes them difficult to read easily if the reader is in any way visually challenged. The book uses good quality paper and is solidly bound.
This book is not for the faint-hearted. It does require an understanding of general and parasite immunology to become really useful, but it should be on the bookshelf of anyone who has an interest in this fascinating and important subject.
RevDr Wayne Melrose, FAIMS, School of Public Health, James Cook University, Townsville, Australia
(Australian Journal of Medical Science, Vol. 28, No. 3, Aug. 2007)


«Das Buch ist allen Spezialisten und Studenten aus den Bereichen der Parasitologie und Allergologie empfohlen, die sich für die Verbindung dieser beiden Fächer - wie uns unser Immunsystem über den IgE schon zeigt - besonders interessieren.»
Arzneimittel-Forschung/Drug Research
A new dimension of host-parasite interactions
The inverse correlation between allergic diseases and helminth infections has been debated for over 30 years. It was initially assumed that the underlying mechanism is an imbalance between Th1 and Th2 responses that, as a result of reduced exposure to Th1-inducing infectious pathogens, has tipped to allergic Th2 responses. It has only recently been clearly demonstrated that helminth infections have negative effects on allergic disease manifestation. This was shown to be consistent with the activity of regulatory cell populations, which control the effector mechanisms of both Th1 and Th2. In this book, international experts in the field discuss the various roles of the cell populations involved in allergic reactions and helminth infections such as regulatory T and B cells, natural killer T cells, mast cells and basophils.
Essential for specialists and students in the field, the contributions to this volume pave the way to new directions of research for the successful immunization against helminths and the prevention of inflammatory responses in allergic and autoimmune diseases.

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