Superantigens and Superallergens

Cover

Editor(s): Marone, G. (Naples)

Status: available   
Publication year: 2007
Buy this book
Print Version : CHF 176.00, EUR 164.00, USD 207.00
Digital Version : CHF 176.00, EUR 164.00, USD 207.00

After ordering this title you will have access to the following digital version:

  • PDF (only downloadable by chapters)

Order this title
The final prices may differ from the prices shown due to specifics of VAT rules, postage and handling.

This book belongs to
Chemical Immunology and Allergy , Vol. 93
Editor(s): Platts-Mills, T.A.E. (Charlottesville, VA)
XIV + 244 p., 42 fig., 1 in color, 5 tab., hard cover, 2007
Status: available   
ISSN: 1660-2242
e-ISSN: 1662-2898


Read the reviews

Reviews

’This volume provides fascinating reviews of the recent work on bacterial and viral superantigens that bind intact to MHC class II molecules and trigger T cells by interacting with the T cell receptor V domain. In addition, studies on B cell superantigens that bind to immunoglobulin and so may activate or lead to apoptosis of B cells are covered…
…The volume is definitely also worthy of institutional purchase and would be a valuable resource for academics, as well as postgraduate and undergraduate students working in the fileds of micrbiology or immunology.’
Ann Pullen, University of Bristol
Microbiology Today, Nov. 2007


’The book is very current, being published in 2007, with recent clinical and molecular findings on the superallergen/superantigen concept. Although it is not a cookbook for diagnostic techniques or any standard operational procedure, it has significance in a wide range of diagnostic principles. It would be of practical relevance in the future as laboratory science advances. The capacity to refresh and update every reader is an immediate benefit. There are intriguing questions that would stir up research, which makes it recommendable especially to researchers and trainers.’
(Australian Journal of Medical Science, vol. 29, No. 2, 2008)
The latest advances at molecular and biochemical levels
Superantigens constitute a growing family of bacterial and viral proteins that share the capacity of inducing massive activation of the immune system. This volume contains contributions from leaders in the field of classical T cell superantigens and sheds light on relevant B cell superantigens at the molecular and biochemical levels. Moreover, articles in this publication deal with the emerging, intriguing possibility that immunoglobulin superantigens can activate primary effector cells of allergic disorders both in vitro and in vivo, thus acting as superallergens. A detailed account is also given of the biochemical, immunological and clinical characteristics of several endogenous, viral and bacterial superallergens, which are probably relevant in a variety of human diseases.
This is the first volume to put together basic and clinical aspects of the classical T cell superantigens, B cell superantigens and superallergens. It will therefore be indispensable reading to basic and clinical immunologists, microbiologists, virologists and specialists in allergic and immune disorders.

Log in to MyKarger to check if you already have access to this title.


TOP