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Reviews
’In summary, modeling exacerbations of asthma and COPD is a growing research subject, and this book provides an excellent overview of the field and the contemporary knowledge of the biology underlying exacerbations. The book should be useful for investigators interested in asthma and COPD exacerbations and who want to model them as part of their research.’
Sanjay Sethi MD, State University of New York at Buffalo, New York
(Respiratory Care, Vol. 53, No. 6, June 2008)
’The book provides an excellent source of information on models of exacerbation of respiratory disease by viral infections. The contributors are all leaders in their respective fields and they discuss both human and animal models. It is much more than just a technical manual, as the authors provide some useful reviews of the topic. I was particularly interested in the epidemiology and annual cycles of exacerbations as the factors driving these cycles are not fully understood. I found the book thought-provoking, and was stimulated to follow up several of the references. The book will be of interest to all those involved in research in asthma and COPD, and could be also be recommended to virologists and epidemiologists in this area. It will be a useful addition to hospital and research libraries, and for those in the field it is a good read.’
Ronald Eccles, Cardiff University
(Microbiology Today, Feb. 2008)
Elucidating the pathobiological processes in chronic airway diseases
This volume provides an overview of exacerbation models of asthma and chronic obstructive pulmonary disease (COPD). Within this wide field the book focuses on experimental systems that mimic pathobiological processes likely to be critical in exacerbations of these conditions.
To generate insight into the mechanisms of exacerbation of pulmonary disease and to promote the discovery of future treatments, both animal models and human experimental models are described. For this update some of the most eminent scientists within the area of pulmonology could be recruited to share their knowledge of this evolving field of human medicine. Models of Exacerbations in Asthma and COPD will be of great interest to pulmonologists, allergologists, specialists in internal medicine and critical care, as well as to microbiologists, infectiologists and pharmacologists studying the response to respiratory infections.
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