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American Journal of Nephrology

Guidelines for Authors

Types of Articles
Conflicts of Interest
Plagiarism Policy
PowerPoint Slides (New Feature)
Color Illustrations
Digital Object Identifier (DOI)
Supplementary Material
Self-Archiving/Green Open Access, Author's ChoiceTM,
   Funding Organizations (NIH etc.)

Page Charges


The 'American Journal of Nephrology' only accepts submissions online.

All further technical instructions can be found there.


The journal will not publish articles which have been previously reported at any length or articles being considered for publication elsewhere. The authors must include a statement to this effect in their cover letter. If publication of the data in any form has occurred or is being contemplated, a copy of such publication should be included with the submitted manuscript. Failure to comply with this directive or discovery of any manuscript text, figure(s), or table(s) duplication will result in immediate retraction of the manuscript and/or article and the authors will not be allowed to submit any future manuscripts to this journal for a period of 3 years.

Submission of an article for publication implies the transfer of the copyright from the author to the publisher upon acceptance.

For legal reasons, we must receive your 'Submission Statement' with your original (hand-written) signature. Please download, print, sign and either fax or scan it to make it legally binding.

It is the author's responsibility to obtain permission to reproduce illustrations, tables, etc. from other publications. The manuscript should be written in English and the editors reserve the right to make appropriate corrections in grammar and style.

Accepted papers become the permanent property of the ‘American Journal of Nephrology’ and may not be reproduced by any means, in whole or in part, without the written consent of the publisher.

Information concerning financial disclosures (i.e. grants, funding, support, etc.) should be placed at the foot of the title page.

Types of Article for Acceptance

(1) Original Reports: Representing full sets of completed experiments in the areas of either clinical or basic research that answer a given question. Max. 5,000 words, incl. references and a maximum of 4 tables and/or figures.

a) Transplantation: Manuscripts under this section include both basic and translational topics. Original experimental data are preferred; however, other content will be considered. Guidelines for this category are similar to the other original reports.
b) Patient-oriented, translational research.
c) Laboratory investigation.

(2) In-Depth Topic Reviews: All In-Depth Topic Reviews agreed upon by the senior editors are invited. If an individual or group has an idea for an in depth review topic, they should email an outline in a word document to the managing editor (bbrisky@medicine.bsd.uchicago.edu) prior to writing the review. PLEASE NOTE: this outline should not be submitted through the journal system. This document should include 1) relevance of review; 2) proposed authors with their institution and areas of expertise; and 3) outline of review headings. The topic will be discussed by senior editors and a decision regarding acceptability reached within 2-3 weeks. If the topic and approach are acceptable, the authors will be granted permission to proceed with submission of the full review through the online system. NOTE: permission to proceed does NOT assure acceptance of the final review article. An Abstract is required and should be divided into Background, Summary and Key Messages. Max. 6,000 words, incl. figures, tables and references.

(3) Novel Research Findings: The focus of these papers is to highlight novel findings as a part of a larger, more comprehensive study. These findings need to be both innovative and potentially helpful to other researchers without compromising the subsequent publication of the author’s primary study. The data can focus on mechanisms related to disease or aspects of clinical management that might extend knowledge and facilitate the research of other investigators. Submissions are limited to 1,500 words with 1 table or figure, maximum 7 references, and an abstract of maximum 100 words stating specifically what the novelty of the findings is.

(4) Invited Editorials: The Editor(s) will invite editorials on specifically selected articles. The editorial will have a maximum of 1,000 words and up to 7 references (one of which should be the paper being reviewed). Also, a maximum of one figure or table is allowed. Also, title of the article which the Invited Editorial is being based on should be included on the Title Page.

Conflicts of Interest

Authors are required to disclose any sponsorship or funding arrangements relating to their research and all authors should disclose any possible conflicts of interest. Conflict of interest statements will be published at the end of the article.


Published research must comply with the guidelines for human studies and animal welfare regulations. Authors should state that subjects have given their informed consent and that the study protocol has been approved by the institute's committee on human research. Further, they should also state that animal experiments conform to institutional standards.

Plagiarism Policy

Plagiarism is misrepresenting somebody else’s published intellectual work-product as your own (Note, this definition excludes ‘self-plagiarism’). In short, it is a misuse of source material. Whether intentional or unintentional, plagiarism is a serious violation of the ‘American Journal of Nephrolo­gy’ policy. Periodically, manuscripts are screened for plagiarism and if your manuscript is found to be consistent with what the Editors define* as plagiarism prior to review of the manuscript then:

1) it will be rejected without review and the author(s) notified as such with a chance for rebuttal.

If a manuscript is found to contain evidence of plagiarism after acceptance and/or publication then:

1) the author(s) will be notified, as in the previous situation, and offered a chance for rebuttal.

If the rebuttal arguments are not found to be satisfactory, as judged by the Editors, the manuscript will be rejected and the author sanctioned from publishing additional papers in the Journal for a period to be determined by the Editorial Board. The period of sanction imposed is dependent on the magnitude of plagiarism with a minimum sanction of one year. If a manuscript already published in the Journal is found to exhibit evidence of plagiarism as defined by the Editors*, then we will request a retraction.
*Definition of plagiarism – a 25% similarity in the Results or Discussion that exactly reproduces another paper.


Title page: The first page of each paper should indicate the title, the authors' names, the institute where the work was conducted, a short title for use as running head, conflict of interest statement, key words, and word count.
Manuscripts are to be double-spaced and formatted using the same font, size 12 throughout text and references.

Full address: The exact postal address of the corresponding author complete with postal code must be given at the bottom of the title page. Please also supply phone and fax numbers, as well as e-mail address.

Key words: Please supply 3–10 key words in English that reflect the content of the paper.

Abstract of Original Reports: Each paper needs an abstract of up to 250 words. It should be organized as follows:
Background: What is the major problem that prompted the study?
Methods: How was the study performed?
Results: Most important findings?
Conclusion: Most important conclusion?

Footnotes: Avoid footnotes.

Abstracts of In-Depth Topic Reviews: Should be divided into the following subsections: Background, Summary and Key Messages. The Background should provide a brief clinical context for the review and is followed by the Summary, which should include a concise description of the main topics covered in the text. The Key Messages encapsulate the main conclusions of the review.

Tables and illustrations: Tables and illustrations (both numbered in Arabic numerals) should be prepared on separate pages. Tables require a heading and figures a legend, also prepared on a separate page. Electronically submitted b/w half-tone and color illustrations must have a final resolution of 300 dpi after scaling, line drawings one of 800–1,200 dpi. Average table = 250 words.
The maximum size of all uploaded files is 40 Mb.

PowerPoint Slides (New Feature)

PowerPoint slides containing figures and tables are made available for Original Reports and In-Depth Topic Reviews after publication. The PowerPoint slides can be downloaded using the dedicated link on the article page.

Color Illustrations

Online edition: Color illustrations are reproduced free of charge. In the print version, the illustrations are reproduced in black and white. Please avoid referring to the colors in the text and figure legends.

Print edition: Up to 6 color illustrations per page can be integrated within the text at CHF 960.00 per page.


In the text identify references by Arabic numerals [in square brackets]. Material submitted for publication but not yet accepted should be noted as ‘unpublished data’ and not be included in the reference list. The list of references should include only those publications which are cited in the text. Do not alphabetize; number references in the order in which they are first mentioned in the text. The surnames of the authors followed by initials should be given. There should be no punctuation other than a comma to separate the authors. Preferably, cite all authors. Abbreviate journal names according to the Index Medicus system. Also see International Committee of Medical Journal Editors: Uniform requirements for manuscripts submitted to biomedical journals (www.icmje.org).


(a) Papers published in periodicals:
Chatel J-M, Bernard H, Orson FM: Isolation and characterization of two complete Ara h 2 isoforms cDNA. Int Arch Allergy Immunol 2003;131:

(b) Papers published only with DOI numbers:
Theoharides TC, Boucher W, Spear K: Serum interleukin-6 reflects disease severity and osteoporosis in mastocytosis patients. Int Arch Allergy Immunol DOI: 10.1159/000063858.

(c) Monographs:
Matthews DE, Farewell VT: Using and Understanding Medical Statistics,
ed 3, revised. Basel, Karger, 1996.

(d) Edited books:
DuBois RN: Cyclooxygenase-2 and colorectal cancer; in Dannenberg AJ, Dubois RN (eds): COX-2. Prog Exp Tum Res. Basel, Karger, 2003, vol 37, pp 124–137.

Reference Management Software: Use of EndNote is recommended for easy management and formatting of citations and reference lists.

Digital Object Identifier (DOI)

S. Karger Publishers supports DOIs as unique identifiers for articles. A DOI number will be printed on the title page of each article. DOIs can be useful in the future for identifying and citing articles published online without volume or issue information. More information can be found at www.doi.org

Supplementary Material

Multimedia files and other supplementary files, directly relevant but not essential to the conclusions of a paper, enhance the online version of a publication and increase its visibility on the web. These files will undergo editorial review. The Editors reserve the right to limit the scope and length of the supplementary material. Multimedia and supplementary material should meet production quality standards for publication without the need for any modification or editing. Files should not exceed 10 MB in size. Figures and tables need to have titles and legends, and all files should be supplied separately and labeled clearly. All supplementary material should be referred to in the main text. A DOI number will be assigned to supplementary material and it will be hosted online at https://karger.figshare.com under a CC BY license.

Self-Archiving/Green Open Access

Karger permits authors to archive their pre-prints (i.e. pre-peer review) or post-prints (i.e. accepted manuscript after peer review but before production) on their personal or their institution’s internal website. In addition, authors may post their accepted manuscripts in public Open Access repositories and scientific networks (e.g. ResearchGate or Mendeley) no earlier than 12 months following publication of the final version of their article. For all self-archiving, the posted manuscripts must:

  • Be used for noncommercial purposes only
  • Be linked to the final version on www.karger.com
  • Include the following statement:

‘This is the peer-reviewed but unedited manuscript version of the following article: [insert full citation, e.g. Cytogenet Genome Res 2014;142:227–238 (DOI: 10.1159/000361001)]. The final, published version is available at http://www.karger.com/?doi=[insert DOI number].’

It is the author’s responsibility to fulfill these requirements.

For papers published online first with a DOI number only, full citation details must be added as soon as the paper is published in its final version. This is important to ensure that citations can be credited to the article.

Manuscripts to be archived in PubMed Central due to funding requirements will be submitted by Karger on the author’s behalf [see Funding Organizations (NIH etc.)].

For self-archiving Author's ChoiceTM (Gold Open Access) articles, see Author's ChoiceTM.

Author's ChoiceTM

Karger’s Author's ChoiceTM service broadens the reach of your article and gives all users worldwide free and full access for reading, downloading and printing at www.karger.com. The option is available for a one-time fee of CHF 3,000.00, which is a permissible cost in grant allocation. More information can be found at www.karger.com/authors_choice.
The final, published version of the article may be posted at any time and in any repository or on other websites, in accordance with the relevant Creative Commons license. Reposted Open Access articles must:

  • Follow the terms of the relevant Creative Commons license
  • Be linked to the final version on www.karger.com
  • Include the following statement:

‘The final, published version of this article is available at http://www.karger.com/?doi=[insert DOI number].’

It is the author’s responsibility to fulfill these requirements.

For papers published online first with a DOI number only, full citation details must be added as soon as the paper is published in its final version. This is important to ensure that citations can be credited to the article.

Funding Organizations (NIH etc.)

The U.S. National Institutes of Health (NIH) Public Access Policy mandates that accepted, peer-reviewed manuscripts are archived in its digital database, PubMed Central (PMC), within 12 months of the official publication date. As a service to authors, Karger submits NIH-funded articles to PMC on behalf of the authors immediately upon publication. The NIH assigns a PMCID within approximately 1 month and the manuscript will appear in PMC after a 12-month embargo. For authors making their paper Open Access through Author's ChoiceTM, the embargo will be overridden, thereby accelerating the accessibility of the article. Karger also complies with other funders’ requirements (including Wellcome Trust and RCUK) for submission to PMC.
Authors should include information on their grant in the Acknowledgements section of their papers.

Page Charges

Original Reports exceeding the first 3 printed pages which are free will cost CHF 410.00 per extra page.


Unless indicated otherwise, proofs are sent to the corresponding author and should be returned with the least possible delay. Alterations made in proofs, other than the correction of printer's errors, as well as corrections after approval to publication, are charged to the author.


Order forms and a price list are sent with the proofs. Orders submitted after the issue is printed are subject to considerably higher prices.